Objectives: To investigate whether adenosine A2A receptors lead to vasodilation and positive inotropic function under stimulation and whether they play a role in the control of blood pressure in patients with cardiogenic shock. Design: Prospective observational study. Setting: Monocentric, Hopital Nord, Marseille, France. Subjects: Patients with cardiogenic shock (n = 16), acute heart failure (n = 16), and acute myocardial infarction (n = 16). Interventions: None. Measurements and Main Results: Arterial adenosine plasma level and A2A receptor expression on peripheral blood mononuclear cells were evaluated by mass spectrometry and Western blot, respectively, at admission and after 24 hours. Hemodynamic parameters, including systemic vascular resistance, were also assessed. Mean adenosine plasma level at admission was significantly higher in patients with cardiogenic shock (2.74 ± 1.03 µM) versus acute heart failure (1.33 ± 0.27) or acute myocardial infarction (1.19 ± 0.27) (normal range, 0.4–0.8 µM) (p
from Emergency Medicine via xlomafota13 on Inoreader https://ift.tt/2toqGz1
Εγγραφή σε:
Σχόλια ανάρτησης (Atom)
Δημοφιλείς αναρτήσεις
-
Archives of Clinical Neuropsychology from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/2eTSYdQ
-
Objective: Many ICU patients do not require critical care interventions. Whether aggressive care environments increase risks to low-acuity p...
-
Timing of Gestation After Laparoscopic Sleeve Gastrectomy (LSG): Does it Influence Obstetrical and Neonatal Outcomes of Pregnancies? Ivor Le...
-
The American Journal of Emergency Medicine from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/2t0g8pt
-
Another great intubation tip from Williamson County EMS. from EMS via xlomafota13 on Inoreader http://ift.tt/2sJ5JQz
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου