OPTIMAL TIMING OF INITIATION OF THROMBOPROPHYLAXIS IN SPINE TRAUMA MANAGED OPERATIVELY: A NATIONWIDE PROPENSITY MATCHED ANALYSIS OF TRAUMA QUALITY IMPROVEMENT PROGRAM

Introduction Patients with spinal trauma are at high-risk for venous-thromboembolism(VTE). Guidelines recommend prophylactic anticoagulation but they are unclear on timing of initiation of thromboprophylaxis. The aim of our study was to assess the impact of early vs late initiation of venous thromboprophylaxis in patients with spinal trauma who underwent operative intervention. Methods We performed a 2-year (2013-14) review of patients with isolated spine trauma (S-AIS≥3 and no other injury in another body region with AIS>2) who underwent operative intervention and received thromboprophylaxis post-operatively. Patients were divided into two groups based on the timing of initiation of thromboprophylaxis: early(

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