Δευτέρα 31 Οκτωβρίου 2016

Midlines

Journal of Critical Care 2014;29:823 Heart & Lung : the Journal of Critical Care 2016 Oct 22; Ultrasound-guided deep-arm veins insertion of long peripheral catheters in patients with difficult venous access after cardiac surgery. Adam Fabiani, Lorella Dreas, Gianfranco Sanson PMID: 27780607

EMCrit by Scott Weingart.



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Midlines

Journal of Critical Care 2014;29:823 Heart & Lung : the Journal of Critical Care 2016 Oct 22; Ultrasound-guided deep-arm veins insertion of long peripheral catheters in patients with difficult venous access after cardiac surgery. Adam Fabiani, Lorella Dreas, Gianfranco Sanson PMID: 27780607

EMCrit by Scott Weingart.



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#DearDaddy

ExEMTNor

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#DearDaddy

ExEMTNor

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#DearDaddy

ExEMTNor

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Emergency Communications Officer - James City County

Emergency Communications Officer I/II Salary dependent on qualifications + Full-Time County Benefits Emergency Communications Officer I - $32,994.00 Emergency Communications Officer II - $35,477.00 Would you like to be a crucial link in public safety" A comprehensive training program is provided to learn the necessary skills for the job. Growth opportunities are available. The job includes quickly ...

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Podcast 185 – Disruption, Danger and Droperidol by Reub Strayer

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Danger, Disruption, and Reub Strayer

EMCrit by Scott Weingart.



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Podcast 185 – Disruption, Danger and Droperidol by Reub Strayer

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Danger, Disruption, and Reub Strayer

EMCrit by Scott Weingart.



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Paramedic - 161501 - Hennepin County Medical Center

The Paramedic position is responsible for responding to requests for emergency medical services and for providing Basic and Advanced Life Support to sick and injured persons at emergency scenes and during transport to a health care facility. We are currently hiring for multiple full-time openings. Schedule will be day/eve/night including rotating weekends and holidays based on department needs. This ...

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How I got through a well-being check

"Haven't seen him in a week," said the man who called us to his home.

Like a lot of folks in the industrial city of Providence, Rhode Island he lived on the second floor of the three level home, rented the first floor to his mom, and the third to whoever answered the ad he posted and seemed decent enough.

"Is that unusual?" I asked.

"He stays to himself mostly, but there's usually some sign of life up there, footsteps, a TV, doors closing, you know."

Yeah, I know. Wish I didn't. I wish I had some Vicks to rub under my nose.

"How old is he?"

"Not too old, 50 maybe," said the man.

Fifty. Not too old. Ha ha. My own 50 years seemed to take a lifetime to reach.

We entered the rear hallway. The stairs led straight up to a landing and a door. There was a shamrock decal stuck there and greasy fingerprints around the doorknob.

"Is that smell normal," I asked the landlord who had followed us?

"He's not the cleanest tenant, but this is bad."

"Yeah, it is."

The landlord opened the door and the smell got worse. A clean stove — not because the tenant was a neatnik, rather it was seldom used. Some empty cans of canned spaghetti and balls of whatever they called meat were on a folding card table that served as his dinette. Dirty dishes spilled out of the sink and onto the counter.

The refrigerator stood in the corner inviting me to open it up. Nothing in there, not even a beer.

"Hello, anybody home?" I shouted, knowing the only answer would be my echo.

He was home alright. I could smell him.

I followed the trail to three doors in a rear hallway. Door number one, door number two or door number three. One of the doors had a string of neckties tied together, starting at the door handle and going over the top.

"Rescue 1 to Fire Alarm, start the police to this address."

"Roger Rescue 1, nature?"

"Possible suicide."

I pushed the middle door. It gave a little but would not open. So I pushed a little harder.

"Here he is."

It was now a crime scene, but I needed to confirm that the man was gone. I got the door open about a foot, squeezed through and watched a dead man's weight force the door shut. He had tied the last of the neckties around his neck, strung the rest over the top of the door, tied the last to the opposite side doorknob, kneeled in front of the door, inside his bedroom, facing the back of the door and closed it.

Slowly?

Quickly?

Did he slam the door?

Did he lean into it?

I couldn't figure out the mechanics of it and realized I was spending way too much time thinking about it. Everything inside him had let go. He was bloated, stiff and dead.

Pictures of a woman and some kids had been pinned to the back of the door. I squeezed back through the doorway, pushing the body with the door.

Thankfully you can look at pictures, but they can't look back.

"Does he have any friends or family?"

"He's lived here for a year, since he got out of prison. Nobody visits that I've seen."

Nobody.

The man at the end of the ties was a lot like the homeless ex-con that had been in the ambulance a few hours before we responded to this home. He was intoxicated, but able to talk. His main concern was finding work. He had no address, no references, no money and no past to put on an application. He had been staying at a shelter, waiting for a break. He seemed like a nice enough guy so I told him about a place my brother, a correctional officer told me about, a place that gave ex-cons a chance.

It is difficult to not judge the people that we meet during our shift. As years in EMS add up, and similar experiences begin to appear the same and the people who make up those experiences say the same things, have the same complaints and even look the same, our empathy can fade. For some EMS providers it takes years while others lose it rather quickly. Then there are those who keep it together for their entire career.

Instead of dwelling on the man who gave up, I was able to focus on the one who looked like a living version of the dead guy, who now had a business name for an apartment and an address in his top pocket. I didn’t know it when I handed the note to him, but the look of gratitude on his face would get me through a difficult call, and the rest of the shift.



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What role do point-of-care devices have in firefighter rehab?

This article first appeared on FireRehab.com, sponsored by Masimo.

By Jay MacNeal with Todd Daniello, Ken Hanson, Mitch Li, Sean Marquis, John Pakiela, Matt Smetana and Chris Wistrom

The ability to rapidly and reliably perform laboratory testing at the patient bedside has taken huge leaps in recent years. There are devices to quickly check a patient's blood sugar, electrolytes, INR, cardiac enzymes, lactic acid and other biomarkers.

Do these devices have a role in the rehab area, or are they only suited for in-hospital care" Glucometers, pulse oximetry, end-tidal carbon dioxide and carbon monoxide (CO) oximetry are all common in EMS, but the use of i-STAT or other point-of-care testing devices is a bit outside the norm of most EMS operations.

To examine the appropriateness of these point-of-care testing options, we must consider the costs and human resources it will require to maintain the processing device, sampling equipment and replacement cartridges, perform calibration and training, obtain CLIA waivers, apply interpretation of the results to immediate patient care and other challenges important to EMS.

With all of that in mind, let’s explore some available point-of-care testing tools and their potential usefulness or application for on-scene rehab of firefighters and other emergency personnel.

ECG and 12-lead EKG
Probably the least frequently used point-of-care test in the rehab environment is the one that has been around the longest. An EKG is an excellent tool in analysis of the person with chest pain or persistent shortness of breath, but it is much more versatile.

By using intervals and morphology of QRS, QTc and T waves we can glean insight into severe electrolyte disturbance, including hypo- or hyperkalemia and hypo- or hypernatremia. Both of these are significant concerns in sports medicine, and it makes sense that we would have the same issues in heat-stressed responders.

One of the steps in risk stratifying patients who have chest pain in the hospital is to subject them to a stress test. This involves exercising or stressing the heart to ensure its ability to maintain adequate perfusion and oxygenation during high demand periods.

Any degree of active or even passive firefighting involves the release of adrenaline and generation and sometimes impaired loss of heat, as well as significant exertion, which all equate to stress on the heart.

Firefighters are at a higher than average risk for heart disease and sudden death than the general population. The complaint of chest pain on the fire scene should most certainly be taken seriously and prompt an appropriate evaluation, including the performance of an on-site 12-lead EKG and timely transport to the hospital for further evaluation.

Lactate levels
The measurement of point-of-care lactic acid levels is an interesting notion. We know that lactic acid is a product of aerobic and anaerobic metabolism. It is found in high levels in those who are hypoperfused, such as sepsis and shock patients [1].

This biomarker as a prehospital point-of-care test is not widely used, but it may become an important assessment tool as mobile integrated health care progresses. Its utility in rehab is uncertain.

CO exposure
Carbon monoxide and cyanide are commonly found in the air on scene of active fires. CO needs to be a concern in confined-space operations as well. Any worker with headache, nausea, vomiting, weakness or altered mental status must be considered for CO exposure.

The Rad-57 is a commonly carried oximeter that will read O2 and CO saturations. It is important to note that whether using Rad-57 for routine CO screening or COHb blood testing in the hospital, a level of CO means almost nothing without a correlating physical examination.

Any patient with symptoms consistent with CO poisoning should be placed on high-flow oxygen and transported for formal laboratory evaluation and thorough workup at the emergency department. Any fire victims or exposed responders with altered mental status should be assumed to have high CO and cyanide levels and need to be aggressively treated.

ETCO2
Carbon dioxide along with water and ATP are produced as a byproduct of cellular metabolism as our bodies consume oxygen and glucose. Following its production, CO2 is transported in the blood and is exhaled through the lungs, where it provides a convenient source to be measured. CO2 measured at the end of an exhaled breath is known as ETCO2.

Basic physiology dictates that as the body becomes more acidic, the carbonic acid buffering system balance shifts toward producing more CO2. A normal ETCO2 is between 35-45 mm Hg. Quantitative ETCO2 is directly related to cardiac perfusion, with a decrease in perfusion leading to a lower ETCO2. A patient with low cardiac output from any number of shock states does not deliver as much CO2 back from the bloodstream to the lungs to be exhaled, which subsequently results in decreased ETCO2 levels.

The use of capnography to measure ETCO2 has been gaining popularity in EMS, with applications from intubation confirmation to sepsis detection. Use of ETCO2 has long been the standard for ventillatory monitoring during anesthesia and procedural sedation.

It is not unrealistic to see ETCO2 utility in firefighter rehab as more and more ALS and BLS services use this technology on a routine basis.

In addition to the quantitative number that is generated, the capnography waveform can also be used to assist in diagnosis of the firefighter in rehab. A bronchospasm waveform is characterized by changes in the ascending phase with loss of the sharp upslope resulting in a shark fin appearance. This is due to uneven emptying of CO2 by the alveoli during exhalation. Correlated with a physical exam, this measurement can also be used to guide treatment and the response to treatment in the firefighter with bronchospasm.

Finally, when using quantitative capnography a respiratory rate is displayed, which can assist in quickly gathering and trending vital signs of firefighters who present to rehab. This saves time and resources over counting respirations, which is frequently inaccurate and time-consuming.

Use of ETCO2 can be an excellent diagnostic aid in the rehab sector of firefighting operations, but remember that diagnostic tests, regardless of their ability and value, must be interpreted in the context of the patient’s clinical picture.

Conclusion
The assessment of anyone going through the rehab process should be dictated primarily by patient history, physical exam and field-proven point-of-care testing. It is unlikely that on-scene labs will be used routinely in the rehab sector unless costs decrease considerably. Pulse oximetry, EKG, ETCO2 and CO oximetry will likely continue to be the mainstays of rehab operations for some time to come.

Having formal rehab protocols, sign-in sheets, individual accountability and the support of incident commanders is crucial to rehab operations. Once in rehab, the responders become the responsibility of those running rehab.

EMS providers who are responsible for rehab operations should be familiar with local EMS protocols and NFPA 1584. In the event that a specific protocol does not cover a condition encountered on scene, medical direction should be contacted and transport initiated. We need to take a conservative approach to protecting the well-being and lives of our responders.

References

1. Hunter et al: End-tidal carbon dioxide is associated with mortality and lactate in patients with suspected sepsis. American Journal of Emergency Medicine (2013) 31, 64–71



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How I got through a well-being check

"Haven't seen him in a week," said the man who called us to his home.

Like a lot of folks in the industrial city of Providence, Rhode Island he lived on the second floor of the three level home, rented the first floor to his mom, and the third to whoever answered the ad he posted and seemed decent enough.

"Is that unusual"" I asked.

"He stays to himself mostly, but there's usually some sign of life up there, footsteps, a TV, doors closing, you know."

Yeah, I know. Wish I didn't. I wish I had some Vicks to rub under my nose.

"How old is he""

"Not too old, 50 maybe," said the man.

Fifty. Not too old. Ha ha. My own 50 years seemed to take a lifetime to reach.

We entered the rear hallway. The stairs led straight up to a landing and a door. There was a shamrock decal stuck there and greasy fingerprints around the doorknob.

"Is that smell normal," I asked the landlord who had followed us"

"He's not the cleanest tenant, but this is bad."

"Yeah, it is."

The landlord opened the door and the smell got worse. A clean stove — not because the tenant was a neatnik, rather it was seldom used. Some empty cans of canned spaghetti and balls of whatever they called meat were on a folding card table that served as his dinette. Dirty dishes spilled out of the sink and onto the counter.

The refrigerator stood in the corner inviting me to open it up. Nothing in there, not even a beer.

"Hello, anybody home"" I shouted, knowing the only answer would be my echo.

He was home alright. I could smell him.

I followed the trail to three doors in a rear hallway. Door number one, door number two or door number three. One of the doors had a string of neckties tied together, starting at the door handle and going over the top.

"Rescue 1 to Fire Alarm, start the police to this address."

"Roger Rescue 1, nature""

"Possible suicide."

I pushed the middle door. It gave a little but would not open. So I pushed a little harder.

"Here he is."

It was now a crime scene, but I needed to confirm that the man was gone. I got the door open about a foot, squeezed through and watched a dead man's weight force the door shut. He had tied the last of the neckties around his neck, strung the rest over the top of the door, tied the last to the opposite side doorknob, kneeled in front of the door, inside his bedroom, facing the back of the door and closed it.

Slowly"

Quickly"

Did he slam the door"

Did he lean into it"

I couldn't figure out the mechanics of it and realized I was spending way too much time thinking about it. Everything inside him had let go. He was bloated, stiff and dead.

Pictures of a woman and some kids had been pinned to the back of the door. I squeezed back through the doorway, pushing the body with the door.

Thankfully you can look at pictures, but they can't look back.

"Does he have any friends or family""

"He's lived here for a year, since he got out of prison. Nobody visits that I've seen."

Nobody.

The man at the end of the ties was a lot like the homeless ex-con that had been in the ambulance a few hours before we responded to this home. He was intoxicated, but able to talk. His main concern was finding work. He had no address, no references, no money and no past to put on an application. He had been staying at a shelter, waiting for a break. He seemed like a nice enough guy so I told him about a place my brother, a correctional officer told me about, a place that gave ex-cons a chance.

It is difficult to not judge the people that we meet during our shift. As years in EMS add up, and similar experiences begin to appear the same and the people who make up those experiences say the same things, have the same complaints and even look the same, our empathy can fade. For some EMS providers it takes years while others lose it rather quickly. Then there are those who keep it together for their entire career.

Instead of dwelling on the man who gave up, I was able to focus on the one who looked like a living version of the dead guy, who now had a business name for an apartment and an address in his top pocket. I didn’t know it when I handed the note to him, but the look of gratitude on his face would get me through a difficult call, and the rest of the shift.



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The association of electrocardiographic abnormalities and major adverse cardiac events in emergency patients with chest pain

Abstract

Objectives

The electrocardiograph (ECG) is an essential tool in initial management and risk stratification of patients with suspected acute coronary syndrome (ACS). A six-point reporting criterion has been proposed to facilitate standardized clinical assessment of patients presenting to the emergency department (ED) with suspected ACS. We set out to evaluate the efficacy of these criteria in identifying patients with major adverse cardiac events (MACE), Type 1 myocardial infarction (T1MI), Type 2 myocardial infarction (T2MI), and one-year mortality in a cohort of emergency patients with chest pain.

Methods

This was an analysis of data from 2349 patients who presented to the Emergency Department with chest pain between 2008-2013. Data were collected as part of two prospective trials. ECGs were recorded at presentation and categorized according to the six-point criteria by local cardiologists blinded to all clinical information. The primary outcome was 30-day MACE, including T1MI, T2MI, unstable angina pectoris, revascularization and 30-day mortality. The outcome was adjudicated by cardiologists on the basis of all clinical information and test results. Likelihood ratios and odds ratios for 30-day MACE were reported for each ECG category.

Results

MACE were diagnosed in 264 (11.3%) patients. Increasing ischemic abnormalities in ECGs, as categorized by the standardized reporting criteria, were associated with increasing rates of MACE. Within 30 days, T1MI occurred in 148 (6.3%) patients and T2MI occurred in 59 (2.5%) patients. Risk for T1MI increased with higher classification of ECG abnormalities. T2MI rates were highest in patients with ECGs of non-specific changes.

Conclusions

The rates of MACE, T1MI and one-year death can be stratified according to standardized ECG criteria in patients presenting to the ED with chest pain. The ECG findings in patients with T2MI are variable, and the ECG is less helpful in defining risk in this group.

This article is protected by copyright. All rights reserved.



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The transition of care between emergency department and primary care: A scoping study

Abstract

Objectives

Patients with chronic diseases often have to seek emergency care for exacerbations. In the face of large predicted increases in the prevalence of chronic diseases, there is increased pressure to avoid hospitalizing these patients at the end of the ED visit, if they can obtain the care they need in the outpatient setting. We performed this scoping study to provide a broad overview of the published literature on the transition of care between ED and primary care following ED discharge.

Methods

We performed a MEDLINE search of English-language articles published between 1990 and March 2015. We created a data-charting form a-priori of the search. Papers were organized into themes, with new themes created when none of the existing themes matched the paper. Papers with multiple themes were assigned preferentially to the theme that was consistent with their primary objectives. We created a descriptive numerical summary of the included studies.

Results

Of 1,138 titles, there were 252 potentially relevant abstracts, and among those 122 met the inclusion criteria for full paper review. An additional 11 papers were acquired from reference review. From the 133 papers, 85 were included in the study. The papers were categorized into seven themes. These included Follow-up compliance and its predictors (38 studies), Telephone calls to discharged ED patients (15 studies), ED navigators (14 studies), The current system (nine studies), Ways to alert primary care providers (PCPs) of the ED visit (seven studies), Patient views and PCP information requirements (one each). In the Follow-up compliance and predictors theme, the two most frequently identified significant predictors for increasing the frequency of follow-up care were the provision of a follow-up appointment time prior to ED departure and the presence of health insurance. Follow-up telephone calls to patients resulted in better follow-up rates, but increased ED return visits in some studies. In the current system patients themselves are the conduit, and the barriers to follow-up care can be high. Email and/or electronic medical record alerts to the PCP are relatively new, and no studies limited the alerts to patients who had a defined need for follow-up care.

Conclusions

A plethora of work has been published on the transition of care from ED to primary care. In order to decrease hospitalizations among the upcoming wave of patients with chronic diseases, it appears that the two most efficient areas to target are a primary care follow-up appointment system and health care insurance. Further research is needed in particular to identify the patients who actually need follow-up care, and to develop information technology solutions that can be effectively implemented within the current emergency healthcare system.

This article is protected by copyright. All rights reserved.



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The effect of frailty on 30-day mortality risk in older patients with acute heart failure attended in the Emergency Department

Abstract

Objective

To determine the effect of frailty on risk of 30-day mortality in non-severely disabled older patients with acute heart failure (AHF) attended in emergency departments (EDs).

Methodology

The Frailty-AHF Study is a retrospective analysis of a multicentre, observational, prospective, cohort study (Older-AHF Register). This study included consecutive patients ≥ 65 years of age without severe functional dependence or dementia attended for AHF in 3 Spanish EDs during 4 months. Frailty was defined by frailty phenotype as the presence of 3 or more domains. Baseline and episode characteristics and 30-day mortality were collected in all the patients.

Results

A total of 465 patients with a mean age of 82 (SD 7) years were included, 283 (61.0%) being female and 225 (51.3%) with severe comorbidity (Charlson index ≥ 3). Frailty was present in 169 (36.3%). The rate of 30-day mortality was 7.3%. Frailty adjusted for potential confounding factors was an independent factor associated with 30-day mortality (adjusted HR=2.5; 95%CI 1.0-6.0; p=0.047).

Conclusion

The presence of frailty is an independent risk factor of 30-day mortality in non-severe dependent older patients attended with AHF in EDs.

This article is protected by copyright. All rights reserved.



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Screening and Treatment for Subclinical Hypertensive Heart Disease in Emergency Department Patients With Uncontrolled Blood Pressure: A Cost Effectiveness Analysis

Abstract

Objectives

Poorly controlled hypertension (HTN) is extremely prevalent and if left unchecked, subclinical hypertensive heart disease (SHHD) may ensue leading to conditions such as heart failure (HF). To address this, we designed a multidisciplinary program to detect and treat SHHD in a high-risk, predominantly African American community. The primary objective of this study was to determine the cost effectiveness of our program.

Methods

Study costs associated with identifying and treating patients with SHHD were calculated and a sensitivity analysis was performed comparing the effect of four parameters on cost estimates. These included prevalence of disease, effectiveness of treatment (regression of SHHD, reversal of left ventricular hypertrophy [LVH], or blood pressure [BP] control as separate measures), echocardiogram costs, and participant time/travel costs. The parent study for this analysis was a single center, randomized controlled trial comparing cardiac effects of standard and intense (<120/80 mm Hg) BP goals at 1 year in patients with uncontrolled HTN and SHHD. A total of 149 patients (94% African American) were enrolled, 133 (89%) had SHHD, 123 (93%) of whom were randomized, with 88 (72%) completing the study. Patients were clinically evaluated and medically managed over the course of one year with repeated echocardiograms. Costs of these interventions were analyzed and, following standard practices, a cost per quality-adjusted life year (QALY) less than $50,000 was defined as cost effective.

Results

Total costs estimates for the program ranged from $117,044 to $119,319. Cost per QALY was dependent on SHHD prevalence and the measure of effectiveness but not input costs. Cost effectiveness (cost per QALY less than $50,000) was achieved when SHHD prevalence exceeded 11.1% for regression of SHHD, 4.7% for reversal of LVH, and 2.9% for achievement of BP control.

Conclusions

In this cohort of predominantly African American patients with uncontrolled HTN, SHHD prevalence was high and screening with treatment was cost effective across a range of assumptions. These data suggest that multidisciplinary programs such as this can be a cost effective mechanism to mitigate the cardiovascular consequences of HTN in ED patients with uncontrolled BP.

This article is protected by copyright. All rights reserved.



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Living with burn scars caused by self-immolation among women in Iraqi Kurdistan: A qualitative study

Burns

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N-acetylcysteine plus deferoxamine for patients with prolonged hypotension does not decrease acute kidney injury incidence: A double blind, randomized, placebo-controlled trial

Critical Care

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Visceral to subcutaneous fat ratio predicts acuity of diverticulitis

Surgical Endoscopy

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Effect of vitamin D supplementation and isokinetic training on muscle strength, explosive strength, lean body mass and gait in severely burned children: A randomized controlled trial

Burns

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Observed long-term mortality after 18,000 person-years among survivors in a large regional drowning registry

Resuscitation

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Evidence of improved efficiency in functional gains during subacute inpatient rehabilitation

American Journal of Physical Medicine & Rehabilitation

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Urinary renalase concentration in patients with preserved kidney function undergoing coronary angiography

Nephrology

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The Impella CP device for acute mechanical circulatory support in refractory cardiac arrest

Resuscitation

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Hydrocortisone treatment in early sepsis-associated acute respiratory distress syndrome: Results of a randomized controlled trial

Critical Care

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Occlusive drainage system for split-thickness skin graft: A prospective randomized controlled trial

Burns

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How veterans with post-traumatic stress disorder and comorbid health conditions utilize e-health to manage their health care needs: A mixed-methods analysis

Journal of Medical Internet Research

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Incidence, characteristics, and survival following cardiopulmonary resuscitation in the quaternary neonatal intensive care unit

Resuscitation

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Risk of Parkinson disease after organophosphate or carbamate poisoning

Acta Neurologica Scandinavica

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Association of brain metabolites with blood lactate and glucose levels with respect to neurological outcomes after out-of-hospital cardiac arrest: A preliminary microdialysis study

Resuscitation

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Predictors of moderate to severe fatigue 12 months following admission to hospital for burn: Results from the burns registry of Australia and New Zealand (BRANZ) long term outcomes project

Burns

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Hypertension after injury among burned combat veterans: A retrospective cohort study

Burns

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Potential target identified for preventing long-term effects of traumatic brain injury

The University of Iowa Health News

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Σάββατο 29 Οκτωβρίου 2016

Acute Kidney Injury in Patients Undergoing the Extracardiac Fontan Operation With and Without the Use of Cardiopulmonary Bypass.

Objectives: To describe the prevalence and risk factors for acute kidney injury in patients undergoing the extracardiac Fontan operation with and without cardiopulmonary bypass, and to determine whether acute kidney injury is associated with duration of mechanical ventilation, cardiovascular ICU and hospital postoperative length of stay, and early mortality. Design: Single-center retrospective cohort study. Setting: Pediatric cardiovascular ICU, university-affiliated children's hospital. Patients: Patients with a preoperative creatinine before undergoing first-time extracardiac Fontan between January 1, 2004, and April 30, 2012. Interventions: None. Measurements and Main Results: Acute kidney injury occurred in 55 of 138 patients (39.9%), including 41 (29.7%) with stage 1, six (4.4%) with stage 2, and eight (5.8%) with stage 3 acute kidney injury. Cardiopulmonary bypass was strongly associated with a higher risk of any acute kidney injury (adjusted odds ratio, 4.8 [95% CI, 1.4-16.0]; p = 0.01) but not stage 2/3 acute kidney injury. Lower renal perfusion pressure on the day of surgery (postoperative day, 0) was associated with a higher risk of stage 2/3 acute kidney injury (adjusted odds ratio, 1.2 [95% CI, 1.0-1.5]; p = 0.03). Higher vasoactive-inotropic score on postoperative day 0 was associated with a higher risk for stage 2/3 acute kidney injury (adjusted odds ratio, 1.9 [95% CI, 1.0-3.4]; p = 0.04). Stage 2/3 acute kidney injury was associated with longer cardiovascular ICU length of stay (mean, 7.3 greater d [95% CI, 3.4-11.3]; p

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Παρασκευή 28 Οκτωβρίου 2016

To SIRS With Love-An Open Letter.

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No abstract available

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Why do some studies find that CPR fraction is not a predictor of survival?

alertIcon.gif

Publication date: November 2016
Source:The Journal of Emergency Medicine, Volume 51, Issue 5
Author(s): Christian Magallanes




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Baclofen Toxicity in a Patient with Hemodialysis-Dependent End-Stage Renal Disease

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Publication date: Available online 24 October 2016
Source:The Journal of Emergency Medicine
Author(s): Lauren M. Porter, Stephanie S. Merrick, Kenneth D. Katz
BackgroundOral baclofen toxicity is extremely rare, but can affect patients with renal disease due to the drug's predominant renal clearance of approximately 69–85%. Patients with severely impaired renal function typically develop symptoms soon after initiating baclofen therapy, even at relatively low doses.Case ReportA 69-year-old woman with a history of hemodialysis-dependent end-stage renal disease presented to the Emergency Department with encephalopathy, ataxia, and dystonia after the addition of a recent baclofen prescription for back pain (10 mg twice daily). She had been taking baclofen as prescribed for approximately 1 week when, the day prior to admission, she had increased her dose to a total of 40 mg. Diagnostic studies demonstrated the patient had chronic, end-stage renal disease and a supratherapeutic concentration of baclofen. Signs and symptoms resolved with hemodialysis.Why Should an Emergency Physician be Aware of This?It is of critical importance for emergency physicians to appreciate impaired baclofen clearance in those with underlying renal disease to obviate the potential for significant drug toxicity.



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Issue Highlights

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Publication date: November 2016
Source:The Journal of Emergency Medicine, Volume 51, Issue 5





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Contents

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Publication date: November 2016
Source:The Journal of Emergency Medicine, Volume 51, Issue 5





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Cost-Effectiveness of HIV Preexposure Prophylaxis for People Who Inject Drugs in the United States

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Publication date: November 2016
Source:The Journal of Emergency Medicine, Volume 51, Issue 5
Author(s): Alexa Camarena-Michel




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Partial Contents of Volume 51, Number 6

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Publication date: November 2016
Source:The Journal of Emergency Medicine, Volume 51, Issue 5





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Advanced Airway Management in an Anesthesiologist-Staffed Helicopter Emergency Medical Service (HEMS): A Retrospective Analysis of 1047 Out-of-Hospital Intubations

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Publication date: November 2016
Source:The Journal of Emergency Medicine, Volume 51, Issue 5
Author(s): Kimberly Hill




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Editorial Board

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Publication date: November 2016
Source:The Journal of Emergency Medicine, Volume 51, Issue 5





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Acetaminophen versus Ibuprofen in Young Children with Mild Persistent Asthma

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Publication date: November 2016
Source:The Journal of Emergency Medicine, Volume 51, Issue 5
Author(s): Christian Magallanes




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Sickle Cell Trait, Rhabdomyolysis, and Mortality Among U.S. Army Soldiers

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Publication date: November 2016
Source:The Journal of Emergency Medicine, Volume 51, Issue 5
Author(s): Sheaffer Gilliam




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Concussion Symptoms and Return to Play Time in Youth, High School, and College American Football Athletes

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Publication date: November 2016
Source:The Journal of Emergency Medicine, Volume 51, Issue 5
Author(s): Kimberly Hill




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Management and Outcomes of Bleeding Events in Patients in the Emergency Department Taking Warfarin or a Non–Vitamin K Antagonist Oral Anticoagulant

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Publication date: Available online 25 October 2016
Source:The Journal of Emergency Medicine
Author(s): Adam J. Singer, Adam Quinn, Neil Dasgupta, Henry C. Thode
BackgroundMost comparisons of bleeding patients who are taking warfarin or a non–vitamin K oral anticoagulant (NOAC) have been limited to admitted patients and major bleeding events in well-controlled, clinical trial settings.ObjectivesWe describe the clinical characteristics, interventions, and outcomes in patients who are taking warfarin or a NOAC who presented to the emergency department (ED) with any bleeding event.MethodsWe conducted a structured, retrospective, observational study of nonvalvular atrial fibrillation, pulmonary embolism, or deep vein thrombosis warfarin- or NOAC-treated patients presenting with any bleeding event to a large, academic ED between January 2012 and March 2015. We used descriptive statistics to summarize baseline characteristics, treatments, and outcomes and performed subgroup analyses based on the type of anticoagulant and site of bleeding.ResultsThe electronic search yielded 95 cases of patients taking a NOAC (i.e., dabigatran [33], rivaroxaban [32], or abixaban [30]) and 342 patients taking warfarin. Reversal agents were rarely used in all anticoagulant groups. Case fatality rates were similar among warfarin- and NOAC-treated patients for gastrointestinal bleeding (7% vs. 7%) and intracranial hemorrhage (18% vs. 4%), respectively. After adjustment for other factors, only intracranial hemorrhage (odds ratio 4.4; 95% confidence interval 1.4–13.3) was associated with mortality.ConclusionsDespite the rare use of reversal strategies, mortality was low and outcomes were comparable among patients with bleeding events presenting to the ED while taking a NOAC compared with warfarin.



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Pediatric Adnexal Torsion: Not Just a Postmenarchal Problem

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Publication date: Available online 24 October 2016
Source:The Journal of Emergency Medicine
Author(s): Abigail M. Schuh, Eileen J. Klein, Rebecca J. Allred, Ana Christensen, Julie C. Brown
BackgroundPediatric adnexal torsion is rare, can be challenging to recognize, and may result in ovarian loss.ObjectiveWe sought to identify and compare the defining characteristics of adnexal torsion in premenarchal and postmenarchal girls.MethodsA retrospective cohort study was performed at a tertiary care children's hospital, including patients diagnosed postnatally with adnexal (ovarian or tubal) torsion between 1997 and 2013. Proportions were compared using relative risk regression.ResultsAdnexal torsion was found in 59 premenarchal and 43 postmenarchal girls. Abdominal pain was the most common chief complaint (54%). History included reports of pain (96%), vomiting (67%), and fever (19%). Excluding 12 patients with isolated tubal torsion and 19 with a teratoma, there were no statistically significant differences in ovarian loss in premenarchal vs. postmenarchal girls (47% and 25% respectively; relative risk [RR] = 1.8 [95% confidence interval {CI} 0.9–3.8]), left- vs. right-sided torsion (47% and 32%; RR = 1.5 [95% CI 0.8–2.7]), pain duration ≤ 2 days vs. > 2 days (31% and 41%; RR = 0.8 [95% CI 0.4–1.5]; n = 64) and severe pain vs. mild to moderate (38% and 33%; RR = 1.1 [95% CI 0.7–1.5]; n = 56).ConclusionsThe diagnosis of pediatric adnexal torsion is difficult and often delayed. Pain and tenderness may not be isolated to a unilateral lower quadrant. Although traditionally considered a postmenarchal problem, in a pediatric academic emergency department adnexal torsion occurred with similar frequency in premenarchal and postmenarchal girls. The potential for organ salvage means that adnexal torsion should be considered in all females presenting with acute abdominal pain regardless of age or menstrual history.



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A text Message Alert System For Trained Volunteers Improves Out-of-Hospital Cardiac Arrest Survival

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Publication date: November 2016
Source:The Journal of Emergency Medicine, Volume 51, Issue 5
Author(s): Alexa Camarena-Michel




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Low Tidal Volume Ventilation Use in Acute Respiratory Distress Syndrome

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Publication date: November 2016
Source:The Journal of Emergency Medicine, Volume 51, Issue 5
Author(s): Alexa Camarena-Michel




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Cerebral Oximetry During Cardiac Arrest: A Multicenter Study of Neurologic Outcomes and Survival

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Publication date: November 2016
Source:The Journal of Emergency Medicine, Volume 51, Issue 5
Author(s): Christian Magallanes




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Derivation of Novel Risk Prediction Scores for Community-Acquired Sepsis and Severe Sepsis

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Publication date: November 2016
Source:The Journal of Emergency Medicine, Volume 51, Issue 5
Author(s): Sheaffer Gilliam




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Dual Defibrillation in Out-of-Hospital Cardiac Arrest: A Retrospective Cohort Analysis

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Publication date: November 2016
Source:The Journal of Emergency Medicine, Volume 51, Issue 5
Author(s): Sheaffer Gilliam




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Cardiac Arrests Associated with Tracheal Intubations in PICUs: A Multicenter Cohort Study

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Publication date: November 2016
Source:The Journal of Emergency Medicine, Volume 51, Issue 5
Author(s): Kimberly Hill




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Calendar

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Publication date: November 2016
Source:The Journal of Emergency Medicine, Volume 51, Issue 5





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Mitochondrial DNA DAMPs in Ventilator Associated Pneumonia: Prevention and reversal by intratracheal DNase I.

Introductions: Previous studies in isolated perfused rat lungs have revealed that endothelial barrier disruption after intra-tracheal administration of pseudomonas aeruginosa (strain 103; PA103) only occurs after accumulation of extracellular mitochondrial DNA (mtDNA) Damage Associated Molecular Patterns (DAMPs) in the perfusate and is suppressed by addition of DNase to the perfusion medium. Herein, we tested the hypothesis that intra-tracheal DNase - a route of administration readily translatable to patient with ventilator-associated pneumonia (VAP) - also enhances degradation of mtDNA and prevents bacteria-induced lung injury. Methods: Intra-tracheal DNase was administered to isolated rat lungs either before or after intra-tracheal challenge with PA103 to determine if bacteria-induced, mtDNA DAMP-dependent lung injury could be prevented or reversed by enhanced mtDNA degradation. To explore whether this concept is translatable to patients with VAP, consecutive patients suspected of VAP were prospectively enrolled. All patients suspected of VAP received a bronchoalvelolar lavage (BAL) with quantitative culture for the diagnosis of VAP. Mitochondrial and nuclear DNA were measured from the BAL. MtDNA DAMPs (i.e. ND6) were measured from serum at time of suspected diagnosis and at 24-48 hours afterward. Results: Intra-tracheal PA103 caused significantly increased the vascular filtration coefficient (Kf) and perfusate mtDNA DAMPs. In contrast, lungs pre- or post-treated with intra-tracheal DNase were protected from increases in Kf and mtDNA DAMPs. Patients with the diagnosis of VAP had significantly higher mtDNA DAMPs in the BAL (248.70+/-109.7 vs 43.91+/-16.61, p

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Outcome of suicidal hanging patients and the role of targeted temperature management in hanging-induced cardiac arrest.

BACKGROUND: No specific treatment is available for hanging-induced cardiac arrest (CA). We hypothesized that targeted temperature management (TTM) may improve the outcome of hanging-induced CA patients at hospital discharge. METHODS: A retrospective chart review of our trauma registry from January 1999 to September 2015 was conducted to identify patients >=18 years with hanging as their injury type. All TTM was performed to achieve 32-34[degrees]C for 24 hours. The survival and Cerebral Performance Category (CPC) scores at hospital discharge were determined. RESULTS: We identified 138 patients. Their average age was 32.1 +/- 10.0; 81.3% were male, and 69.8% were Caucasian. The mortality rate was 15.2% (21/138). Overall, 79.7% (110/138) of the near-hanging patients did not sustain out-of-hospital CA (non-CA), and 1.8% of them (2/110) received TTM. All 110 non-CA patients survived to hospital discharge and 99.1% (109/110) had good neurologic outcome. The remaining 20.3% (28/138) of hanging patients suffered out-of-hospital CA; 6 of these patients were dead-on-arrival and thus excluded from further analysis. TTM was performed for 40.9% (9/22) of the remaining CA patients; 44.4% (4/9) of TTM CA patients survived to hospital discharge versus 23.1% (3/13) of non-TTM CA patients. There were no significant differences between the overall survival and patients discharged with good neurologic outcome between the TTM and non-TTM CA groups. CONCLUSIONS: Non-CA near-hanging patients are more likely to have favorable outcome than the CA patients. Our study was not large enough to detect survival and neurologic outcome differences between the TTM and non-TTM CA groups. A multicenter retrospective study is underway to determine the impact of TTM on the outcome of hanging-induced CA patients. LEVEL OF EVIDENCE: Therapeutic study, level IV; prognostic study, level IV (C) 2016 Lippincott Williams & Wilkins, Inc.

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Management of adult pancreatic injuries: A practice management guideline from the Eastern Association for the Surgery of Trauma.

Background: Traumatic injury to the pancreas is rare but is associated with significant morbidity and mortality, including fistula, sepsis, and death. There are currently no practice management guidelines for the medical and surgical management of traumatic pancreatic injuries. The overall objective of this article is to provide evidence-based recommendations for the physician who is presented with traumatic injury to the pancreas. Methods: The MEDLINE database using PubMed was searched to identify English language articles published from January 1965 to December 2014 regarding adult patients with pancreatic injuries. A systematic review of the literature was performed, and the Grading of Recommendations Assessment, Development and Evaluation (GRADE) framework was employed to formulate evidence-based recommendations. Results: Three hundred nineteen articles were identified. Of these, 52 papers underwent full text review and 37 were selected for guideline construction. Conclusions: Patients with grade I/II injuries tend to have fewer complications; for these, we conditionally recommend nonoperative or non-resectional management. For grade III/IV injuries identified on CT or at operation, we conditionally recommend pancreatic resection. We conditionally recommend against the routine use of octreotide for post-operative pancreatic fistula prophylaxis. No recommendations could be made regarding the following two topics: optimal surgical management of Grade V injuries; and the need for routine splenectomy with distal pancreatectomy. (C) 2016 Lippincott Williams & Wilkins, Inc.

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Damage control surgery in weightlessness: A comparative study of simulated torso hemorrhage control comparing terrestrical and weightless conditions.

Introduction: Torso bleeding remains the most preventable cause of post-traumatic death worldwide. Remote Damage Control Resuscitation (RDCR) endeavours to rescue the most catastrophically injured, but has not focused on pre-hospital surgical torso haemorrhage control (HC). We examined the logistics and metrics of intra-peritoneal packing in weightlessness in Parabolic flight (0g) compared to terrestrial gravity (1g) as an extreme example of surgical RDCR. Methods: A surgical simulator was customized with high-fidelity intra-peritoneal anatomy, a "blood" pump and flow-meter. A standardized HC task was to explore the simulator, identify "bleeding" from a previously unknown liver injury perfused at 80 mmHg, and pack to gain hemostasis. Ten surgeons performed RDCR laparotomies onboard a research aircraft, first in 1g followed by 0g. The standardized laparotomy was sectioned into 20 second segments to conduct and facilitate parabolic flight comparisons, with "blood' pumped only during these time-segments. A maximum of 12 segments permitted for each laparotomy. Results: All 10 surgeons successfully performed HC in both 1g and 0g. There was no difference in blood loss between 1g and 0g (p=0.161) or during observation following HC (p=0.944). Compared to 1g, identification of bleeding in 0g incurred less "blood" loss (p=0.032). Overall surgeons rated their personal performance and relative difficulty of surgery in 0g as "harder" (median Likert 2/5). However, conducting all phases of HC were rated equivalent between 1 and 0g (median Likert 3/5), except for instrument control (rated slightly harder 2.75/5). Conclusion: Performing laparotomies with packing of a simulated torso hemorrhage in a high-fidelity surgical simulator was feasible onboard a research aircraft in both normal and weightless conditions. Despite being subjectively "harder" most phases of operative intervention were rated equivalently, with no statistical difference in "blood" loss in weightlessness. Direct Operative control of torso hemorrhage is theoretically possible in extreme environments if logistics are provided. Level of Evidence: IV (C) 2016 Lippincott Williams & Wilkins, Inc.

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Utility of the injured trauma survivor screen to predict PTSD and depression during hospital admission.

Background: The brief, easily administered screen, the Injured Trauma Survivor Screen (ITSS) was created to identify trauma survivors at risk for development of posttraumatic stress disorder (PTSD) and depression. Methods: An item pool of PTSD risk factors was created and given, along with a previously created screen, to patients admitted to two level 1 trauma centers. The Clinician Administered PTSD Scale for DSM-5, the PTSD Checklist for DSM-5, and the Center for Epidemiological Studies Depression Scale Revised were given during a one-month follow-up. 139 participants were included (n = 139; [mu] age = 41.06; 30.9% female; 47.5% White/Caucasian; 39.6% Black/African American; 10.1% Latino/Hispanic; 1.4%; American Indian; and 1.4% other). Stepwise bivariate logistic regression was used to determine items most strongly associated with PTSD and depression diagnosis one-month post injury. Results: 40 participants met criteria for a PTSD diagnosis and 28 for depression at follow-up (22 comorbid). ROC curve analysis was used to determine sensitivity (PTSD = 75.00, Depression = 75.00), specificity (PTSD = 93.94, Depression = 95.5), NPV (PTSD = 90.3, Depression = 80.8) and PPV (PTSD = 83.3, Depression = 93.8) of the final nine item measure. Conclusions: This study provides evidence for the utility of a predictive screen, the ITSS, to predict which injured trauma survivors admitted to the hospital are at the most risk for developing symptoms of PTSD and depression one-month post injury. The ITSS is a short, easily administered tool that can aid in reducing the untreated cases of PTSD and depression. Level of Evidence: Prognostic study, Level III. (C) 2016 Lippincott Williams & Wilkins, Inc.

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Traumatic Muscle Fibrosis: From Pathway to Prevention.

Muscle fibrosis, the disruption, of functional parenchyma by stromal elements, is an often overlooked sequela of traumatic muscle injury, ageing, and congenital disease. The remarkable regenerative capacity of skeletal muscle is dependent on the interaction of myogenic progenitors and the same stromal connective tissue elements responsible for fibrosis generation and propagation. The coordination of effective therapeutic strategies to mitigate muscle fibrosis following injury requires a clear understanding of the prominent cellular progenitors, extracellular constituents, and signaling mechanisms involved in muscle healing. Recent studies have begun to elucidate the critical cellular processes that delineate physiologic regeneration and dysregulated healing resulting in muscle fibrosis. This review presents the salience of these novel findings in the context of the current treatment paradigms for muscle fibrosis. (C) 2016 Lippincott Williams & Wilkins, Inc.

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Temporary abdominal closure for trauma and intra-abdominal sepsis: different patients, different outcomes.

Background: Temporary abdominal closure (TAC) following damage control surgery (DCS) for injured patients has been generalized to septic patients. However, direct comparisons between these populations are lacking. We hypothesized that patients with intra-abdominal sepsis would have different resuscitation requirements and lower primary fascial closure rates than trauma patients. Study Design: We performed a three year retrospective cohort analysis of patients managed with TAC for trauma (n=77) or intra-abdominal sepsis (n=147). All patients received negative pressure wound therapy (NPWT) TAC with intention for planned relaparotomy and sequential abdominal closure attempts at 24-48 hour intervals. Results: At presentation, trauma patients had higher rates of hypothermia (31% vs. 18%), severe acidosis (27% vs. 14%), and coagulopathy (68% vs. 48%), and septic patients had higher vasopressor infusion rates (46% vs. 27%). Forty-eight hours after presentation, septic patients had persistently higher vasopressor infusion rates (37% vs. 17%), and trauma patients had received more red blood cell transfusions (6.0 vs. 0.0 units), fresh frozen plasma (5.0 vs. 0.0 units), and crystalloid (8,290 vs. 7,159 ml). Among patients surviving to discharge, trauma patients had higher primary fascial closure (PFC) rates (90% vs. 76%). For trauma patients, independent predictors of failure to achieve PCF were >=2.5 L NPWT output at 48 hours, >=10 L crystalloid administration at 48 hours, and >=10 U PRBC+FFP at 48 hours. For septic patients, relaparotomy within 48 hours predicted successful PFC; requirement for >=3 diagnostic/therapeutic laparotomies predicted failure to achieve PFC. Conclusions: Traumatic injury and intra-abdominal sepsis are associated with distinct pathophysiologic insults, resuscitation requirements, and outcomes. Failure to achieve primary fascial closure in trauma patients was attributable to the triad of hypothermia, acidosis, and coagulopathy; failure to achieve fascial closure in septic patients was dependent upon operative course. Indications and optimal techniques for TAC may differ between these populations. Level of Evidence: level IV - therapeutic, and level III - prognostic (C) 2016 Lippincott Williams & Wilkins, Inc.

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Assessment of key plasma metabolites in combat casualties.

Background: Previous studies have indicated that hemorrhagic shock and injury cause significant early changes in metabolism. Recently, global changes in metabolism have been described using metabolomics in animal models and civilian trauma. We evaluated metabolic changes associated with combat injury to identify early biomarkers and aid in triage. Methods: Plasma obtained at Emergency Department (ED) presentation and intervals thereafter from patients injured during combat operations in Iraq (n=78) were compared to healthy control subjects (n=40). Using proton Nuclear Magnetic Resonance, water-soluble metabolites were detected and quantified. Resulting metabolic profiles were analyzed with partial least squares discriminant analysis (PLS-DA), ROC, and cluster analyses to identify features of combat injury and mortality. Results: Significant alterations to metabolism resulted from traumatic injury. Metabolic profiles of injured patients differed from those of healthy controls, driven by increased 5-aminolevulinate and hypoxanthine that persisted through 24 hours. Among combat-injured patients, increased succinate and malonate best discriminated between those who survived from those who did not. Higher levels of succinate and hypoxanthine were associated with increased injury severity. ROC analysis showed that these metabolites had equivalent or superior performance to lactate in distinguishing the presence of trauma, injury severity, and mortality. Conclusions: Combat injury is associated with several changes at the metabolic level compared to healthy individuals. Novel potential biomarkers of mortality (succinate, malonate), injury severity (succinate, hypoxanthine), and the presence of trauma (hypoxanthine, 5-aminolevulinate) perform as well as or better than the common clinical standard, lactate. Level of Evidence: Level III Study Type: Prognostic (C) 2016 Lippincott Williams & Wilkins, Inc.

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Why EMS needs more protection on roadway incidents

Roadways are the most dangerous scene types for EMS providers and require increased safety measures from hazardous exposure to minimize death and serious injury of public safety personnel.

We regularly share news stories of fire apparatus struck while attending a motor vehicle collision, EMS providers struck while tending to a patient and police officers killed after stopping a speeding driver or checking on a disabled vehicle.

In late October, a medical helicopter was struck and tipped over in New Mexico by an intoxicated driver who drove around barricades meant to block traffic. The reckless driver also hit a fire truck. No injuries were reported, but we don't know the impact of the transport delay on the patient's outcome. We also don't know the potential impact of traumatic stress on the EMS and fire personnel who were in the midst of caring for a patient when a out-of-control vehicle plowed into their scene.

Six months ago, nearly to the day, another medical helicopter was struck by a drunk driver who swerved through emergency vehicles before striking the helicopter's tail rotor. The impact of this central Florida incident on the patient's outcome, as well as the emergency responders, is unknown.

Because of the frequency with which emergency personnel, vehicles and now helicopters are struck, we need to accept that erecting barricades, parking a couple of blocking vehicles, waving orange flags or setting-up temporary signs is inadequate scene protection. High-visibility apparel looks great, but if the fire truck and flashing lights don't get a drunk or distracted driver's attention, then a neon-reflective vest is the equivalent of an invisible cloak.

Roadway is a hazardous materials hot zone
Any time you are working on or near a roadway, you are in the hot zone of a hazardous materials incident. Vehicles, blunt trauma-inflicting machines, hurtle around you under the loose control of undertrained, often impaired and often distracted operators. Protect your life, livelihood and family's future by protecting yourself with time, distance and shielding.

Time: As little as possible
A lethal dose exposure on a roadway can happen in a fraction of a second. Minimize EMS personnel exposure by clearing the patient to an area of relative or improved safety as quickly as possible. Pick helicopter landing zones with limited and securable access.

A firefighter injured in a structure fire is not treated in the midst of the flames and smoke — a highly hazardous and unstable environment. Instead, the firefighter is evacuated quickly and aggressively out of the structure. The awaiting ambulance or helicopter is parked well outside of the building's collapse zone. Start visualizing any roadway incident as a fully-involved, multiple story structure fire.

Distance: Get out of the striking zone
Visual warnings — signs, flares, spotters — to drivers are nice, but not enough. Increase the frequency, visual loudness and upstream distance of warning signs from the incident.

It's even better to get out of the striking zone. Move the ambulance off the road as quickly as possible. Load and go to a parking lot, access road or location that is well outside of the striking range of impaired and reckless drivers. Find and use landing zones that are not within the accessible distance of a driver.

Shielding: Bigger and stronger wall
If personnel are stuck on the road because the patient requires prolonged extrication, build a bigger and stronger wall that is impenetrable by motor vehicles. If the opportunity exists to go around, through or over the wall of blocking vehicles, we can be sure that a determined, distracted or impaired driver will make an attempt to break through the shielding.

Finally, our brains are wired to see what we are expecting to see and poorly wired to see what we are not expecting. If you have ever driven west across South Dakota, you know that there are Wall Drug signs every few miles. Because your brain is expecting Wall Drug signs, you see nearly every one regardless of its size, distance from the road or message.

Very few drivers are ever overtaken by an emergency vehicle and thus often default to blissful unawareness or fight-or-flight driven erratic movement. Even fewer drivers are expecting a helicopter to be parked on the center line. Don't expect or rely on their impaired or distracted cognitive function to identify and react appropriately to this unexpected and never before encountered environmental change.



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Risk factors for new-onset delirium in patients with bloodstream infections: independent and quantitative effect of catheters and drainages—a four-year cohort study

Bloodstream infections (BSI) and delirium are frequent in critically ill patients. During systemic inflammatory response to BSI, cytokines may interact with neurotransmitters and neuronal receptors driving acu...

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Myocardial function at the early phase of traumatic brain injury: a prospective controlled study

The concept of brain-heart interaction has been described in several brain injuries. Traumatic brain injury (TBI) may also lead to cardiac dysfunction but evidences are mainly based upon experimental and clini...

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Physical function and pain after surgical or conservative management of multiple rib fractures – a follow-up study

There is scarce knowledge of physical function and pain due to multiple rib fractures following trauma. The purpose of this follow-up was to assess respiratory and physical function, pain, range of movement an...

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Cognitive rest and graduated return to usual activities versus usual care for mild traumatic brain injury: A randomized controlled trial of emergency department discharge instructions

Abstract

Introduction

It is estimated 15-25% of patients with a mild traumatic brain injury (MTBI) diagnosed in the emergency department (ED) will develop post-concussive syndrome (PCS). The objective of this study was to determine if patients randomized to graduated return to usual activity discharge instructions had a decrease in their Post-Concussion Symptom Score (PCSS) 2 weeks after MTBI compared to patients who received usual care MTBI discharge instructions.

Methods

This was a pragmatic, randomized trial of adult (18-64 years) patients of an academic ED (annual census 60,000) diagnosed with MTBI occurring within 24 hours of ED visit. The intervention group received cognitive rest and graduated return to usual activity discharge instructions, and the control group received usual care discharge instructions that did not instruct cognitive rest or graduated return. Patients were contacted by text message or phone 2 and 4 weeks post ED discharge and asked to complete the PCSS, a validated, 22 item questionnaire, to determine if there was a change in their symptoms. Secondary outcomes included change in PCSS at 4 weeks, number follow-up physician visits, and time off work/school.

Results

118 patients were enrolled in the study (58 in the control group and 60 in the intervention). Mean age was 35.2 (13.7) years and 43 (36.4%) were male. There was no difference with respect to change in PCSS at 2 weeks (10.5 vs 12.8; ∆ 2.3, 95% CI: 7.0, 11.7) and 4 weeks post-ED discharge (21.1 vs 18.3; ∆ 2.8, 95% CI: 6.9, 12.7) for the intervention and control groups, respectively. The number follow-up physician visits and time off work/school was similar when the groups were compared. Thirty-eight (42.2%) and 23 (30.3%) of patients in this cohort had ongoing on-going MTBI symptoms (PCSS > 20) at 2 weeks and at 4 weeks, respectively.

Conclusions

Results from this study suggest graduated return to usual activity discharge instructions do not impact rate of resolution of MTBI symptoms 2 weeks after ED discharge. Given patients continue to experience symptoms 2 and 4 weeks after MTBI, more investigation is needed to determine how best to counsel and treat patients with post-concussive symptoms.

This article is protected by copyright. All rights reserved.



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A case of cardiac arrest that occurred on a high mountain in which a favorable outcome was obtained

The American Journal of Emergency Medicine

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Epigenetic regulation of early- and late-response genes in acute pancreatitis

The Journal of Immunology

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Ventricular-arterial coupling and exercise-induced pulmonary hypertension during low-level exercise in heart failure with preserved or reduced ejection fraction

Journal of Cardiac Failure

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Diagnostic performance of delta cardiac troponin levels for acute non-ST-elevation myocardial infarction

JACC - Journal of the American College of Cardiology

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Central Nervous System toxicity of mefenamic acid overdose compared to other NSAIDs: An analysis of cases reported to the United Kingdom National Poisons Information Service.

British Journal of Clinical Pharmacology

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Blood cultures and bacteraemia in an Australian emergency department: Evaluating a predictive rule to guide collection and their clinical impact

Emergency Medicine Australasia

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Regional nerve blocks improve pain and functional outcomes in hip fracture: a randomized controlled trial

Journal of the American Geriatrics Society

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Serum potassium levels and outcome in acute heart failure. (data from the protect and coach trials)

The American Journal of Cardiology

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Intrauterine balloon tamponade for management of severe postpartum haemorrhage in a perinatal network: A prospective cohort study

BJOG: An International Journal of Obstetrics and Gynaecology

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Relation between lymphocyte to monocyte ratio and short-term mortality in patients with acute pulmonary embolism

The Clinical Respiratory Journal

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Conversion to shockable rhythms during resuscitation and survival for out-of hospital cardiac arrest

The American Journal of Emergency Medicine

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Longitudinal patterns of emergency department visits: A multistate analysis of Medicaid beneficiaries

Health Services Research

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The development and psychometric evaluation of a supplementary index score of the neuropsychological assessment battery screening module that is sensitive to traumatic brain injury

Archives of Clinical Neuropsychology

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Robotic near-total pancreatectomy for nesidioblastosis after bariatric surgery

Obesity Surgery

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Systematic review and meta-analysis of first-pass success rates in emergency department intubation: Creating a benchmark for emergency airway care

Emergency Medicine Australasia

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Successful treatment of small intestinal bleeding in a Crohn's patient with noncirrhotic portal hypertension by transjugular portosystemic shunt placement and infliximab treatment

Case Reports in Gastroenterology

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Πέμπτη 27 Οκτωβρίου 2016

Globe, DuPont, and NVFC announce more winners in 2016 Gear Giveaway

A total of 52 sets of gear will be awarded in 2016 Globe, DuPont Protection Solutions (DuPont), and the National Volunteer Fire Council (NVFC) have announced the latest round of winners in the 2016 Globe Gear Giveaway. This is the fifth year that Globe has partnered with DuPont and the NVFC to provide volunteer departments with critically needed sets of turnout gear. The Northwest Washington Volunteer ...

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Ada County Paramedics ABC PSA

According to Ada County Paramedics call 911 call volume records, there were 15 infant sleep-related deaths since 2010, which is roughly two infant deaths each year.

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Ada County Paramedics ABC PSA

According to Ada County Paramedics call 911 call volume records, there were 15 infant sleep-related deaths since 2010, which is roughly two infant deaths each year.

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Ada County Paramedics ABC PSA

According to Ada County Paramedics call 911 call volume records, there were 15 infant sleep-related deaths since 2010, which is roughly two infant deaths each year.

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Substance abuse programs: What EMTs and paramedics need to know

Don Prince is a former fire chief, firefighter and EMS provider. He's also a recovering alcoholic, which is why he's a former fire chief, no longer a fire department member and not providing EMS care. In an article Prince wrote:

"One of the biggest things I could not let go of was my embarrassment, disappointment in myself and shame of having to resign my position as chief and my membership after almost 17 years of being a part of something that meant so much to me and for which I was not willing or able to make a choice to correct in order to try and save. Drinking was more important than my career and family at that time. I now see that if I had addressed my addiction years ago and sought the help that was offered to me none of this would have happened [1]."

Some EMS providers just like the patients they serve struggle with alcoholism and addiction. The daily stress of EMS work, as well as some cultural norms, may cause some EMS providers to unwind with friends and colleagues in situations where alcohol flows freely.

Research on alcohol use in EMS and fire
Science defines binge drinking as five or more servings for men or four or more servings for women. The definition is based on blood alcohol content — that consuming that many drinks within two hours typically raises BAC to 0.08 g/dL or higher [2].

In a study, funded by a grant from Federal Emergency Management Agency's Research and Development, firefighters were asked about their alcohol use. Data was collected from 656 male firefighters from 24 departments in the Missouri Valley region [3].

  • Of the firefighters surveyed, 85 percent of career and 71 percent of volunteer firefighters reported drinking alcohol in the past 30 days.
  • Approximately half of career and volunteer firefighters reported binge drinking in the past month.
  • Career firefighters reported drinking 10 days per month, which is about half their off-duty days in most departments.
  • Volunteer firefighters reported drinking an average of 12 days a month.

So, how do firefighters compare to the general male population in the United States" According to the 2013 National Survey on Drug Use and Health, 62 percent of males reported consuming alcohol in the past month — significantly lower than the fire service [4].

In 2010, the Centers for Disease Control and Prevention published data on binge drinking from more than 176,000 males. They found that 23 percent of males reported binge drinking in the month previous — half the rate of binge drinking reported in the fire service research [5].

We also know from anecdotal news reports, social media sharing and personal observation that EMS providers and firefighters seek solitude in the privacy of their own home in the company of a bottle of wine, beer or spirits. For a handful of addicts, the access to patient and agency medications can lead to a downward spiral of narcotics abuse, addiction and theft.

Substance treatment programs
The goal of substance abuse treatment is to stop drug or alcohol abuse and allow addicts to lead active lives in their family, workplace and community. One continual challenge, however, is keeping patients in treatment long enough for them to achieve this goal. That is why finding the right treatment for a person's specific needs is critical.

Drug abuse treatment is not one size fits all. Treatment outcomes depend on the [7]:

  • Extent and nature of the person's problems
  • Appropriateness of treatment
  • Availability of additional services such as after-care
  • Quality of interaction between the person and his or her treatment providers

To help addicts find appropriate care, the National Institute on Drug Abuse created a brief guide that asks five questions to answer when searching for a treatment program [8]:

  1. Does the program use treatments backed by scientific evidence"
  2. Does the program tailor treatment to the needs of each patient"
  3. Does the program adapt treatment as the patient's needs change"
  4. Is the duration of treatment sufficient"
  5. How do 12-step or similar recovery programs fit into drug addiction treatment"

Information resources on drug and alcohol addiction
The Substance Abuse and Mental Health Services Administration is the agency within the U.S. Department of Health and Human Services that leads public health efforts to advance the behavioral health of the nation. SAMHSA's mission is to reduce the impact of substance abuse and mental illness on America's communities.

One of SAMHSA’s programs is the National Registry of Evidence-based Programs and Practices, a repository and review system designed to provide the public with reliable information on mental health and substance abuse interventions. All interventions in the registry have met NREPP's minimum requirements for review. The programs' effects on individual outcomes have been independently assessed and rated by certified NREPP reviewers [9].

The Joint Commission is an independent, not-for-profit organization that accredits and certifies nearly 21,000 health care organizations and programs in the United States. The Joint Commission accreditation and certification of substance abuse treatment centers is recognized nationwide as a symbol of quality that reflects an organization’s commitment to meeting certain performance standards [10].

Addiction treatment programs
A variety of treatment options are available. Some treatment programs serve a diverse patient population while others focus their efforts on the specific characteristics of public safety personnel.

The Watershed is an addiction treatment program, licensed by the Florida Department of Children and Families, Substance Abuse Program Office and accredited by the Better Business Bureau. The Watershed also maintains Gold Seal accreditation through The Joint Commission. The Watershed has provided inpatient addiction, detoxification and rehabilitation services for over 14 years and successfully treated over 35,000 people [11].

The Watershed Addiction Treatment Programs website includes a wealth of resource including links for treatment programs in each of the 50 U.S. states.

In just three years, the Brattleboro Retreat Uniformed Service Program in Vermont has helped about 1,200 uniformed service professionals deal with issues including stress, substance abuse, trauma and depression [12]. Participants come to Brattleboro from throughout the United States, as well as military bases in Europe.

The Brattleboro Uniformed Service Program is a rigorous, brief — average stay is 10 days — partial hospitalization program for active or retired members of a uniformed service, such as police, fire, corrections, military and emergency medical service. Its structured and supervised psychotherapy program focuses on rapid clinical change, reduction of symptoms and stabilization and transitioning to outpatient service providers [13].

American Addiction Centers owns and operates adult drug and alcohol treatment and rehabilitation facilities nationwide. AAC has treatment facilities located in California, New Jersey, Florida, Texas, Nashville and Las Vegas [14].

The Rosecrance Florian Program for firefighters and paramedics incorporates occupational factors into the treatment process. The program’s director is an active-duty Battalion Chief/EMT with more than 25 years of experience with the Chicago Fire Department. Operational medical control is provided by a board-certified psychiatrist and addictionologist who is trained and experienced in treating firefighters and paramedics for co-occurring disorders [15].

Do your research
Don Prince, the former fire chief, took his new "lease on life" as a recovering alcoholic and sought training and education from The Addictions Academy to become a Certified Recovery Coach and Interventionist through. The Addictions Academy is one of the nation’s leading and accredited centers for individuals seeking training and certification in the fields of addiction treatment services, recovery/sober coaching and intervention.

During my e-mail exchange with Prince, he expressed the need for EMS providers looking for substance abuse treatment options to be cautious. "I would like to share with you my opinion of what the truth is as far as what is out there for one of us who needs help. It is not a very good situation given the current state of the substance abuse industry." [16].

Regarding some residential treatment facilities, Prince wrote, "The idea that a majority of the providers are in it to save lives and help you is not their primary intended mission. That comes secondary to filling beds and making a profit. What suffers is the quality of care during your stay at a facility and, even more importantly, is the lack of aftercare when you leave and get home and back on the job."

According to Prince, 80 percent of people leaving an addiction treatment center relapse within the first year of discharge. Nine out of ten of the addicts who relapse do so within their first 90 days after discharge. "Working with a Recovery Coach can significantly reduce the likelihood of relapse during this crucial period," wrote Prince. "Recovery Coaching is often the missing link, bridging the gap between an individual leaving a treatment center and maintaining long term sobriety."

References
1. Prince, D. Fighting the Devil Within. [Available: On-line] http://ift.tt/2fj3rlF"trk=mp-reader-card

2. FireRescue1. Firefighters and alcohol, what the data says. http://ift.tt/2ePVZLS

3. Ibid.

4. Ibid.

5. Ibid.

6. National Institute on Drug Abuse (NIDA/NIH). Anyone Can Become Addicted to Drugs. YouTube. https://youtu.be/SY2luGTX7Dk

7. National Institute on Drug Abuse. Seeking Drug Abuse Treatment: Know What to Ask. http://ift.tt/24uY7io

8. Ibid.

9. Substance Abuse and Mental Health Services Administration. National Registry of Evidence-based Programs and Practices. http://ift.tt/1SIOoyj

10. The Joint Commission. About The Joint Commission. http://ift.tt/1kWWHXK

11. The Watershed Addiction Treatment Programs. Frequently Asked Questions. http://ift.tt/2ePXb1W

12. Brattleboro Retreat. Uniformed Service Program. http://ift.tt/2fj7vC8

13. New England Psychologist. Program helps service professionals. http://ift.tt/2ePZNgm

14. American Addiction Centers. Frequently Asked Questions. http://ift.tt/2fj3wph

15. Rosecrance Florian Program. Firefighter & Paramedic Substance Abuse Treatment Program. http://ift.tt/2ePZa6r

16. Prince, D. Personal Communication via LinkedIn. April 14, 2016.



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When EMS calls leave you with a feeling of emptiness

By Anonymous Paramedic, Sacramento, Calif.

Some days it's a lot to handle. It's a hard thing to describe. I've never been one for talking about my feelings. The more important it is, the more powerful the feeling, the less I will say about it. The best I can do is to say that it is a feeling of crushing emptiness.

There is always a lot of talk about how this job can effect us. People die while we try to keep them from doing so. That is definitely a humbling feeling. I have worn other people's blood on my skin. I have heard the last words of people I have just met. I have felt my paradigm shift, and my ego crumble when I realize that I cannot help my patient and I do not know why.

I have experienced many of the stereotypical, harrowing experiences associated with this profession. I do not mean to underestimate the effects that those experiences can have on us, but for me personally it feels a little self-aggrandizing.

Those are the stories people expect.

When someone sees me staring into space, lost in my thoughts, it's easy for them to imagine those things running through my mind. I wish that were the case.

Make no mistake, I am struggling.

This job does eat away at me every day. There have been days that the toll is taken in one fell swoop, with a fast-paced, high pressure, traumatizing call.

Most days that isn't the case. Most days I don't have such a convenient target to point at when those feelings hit me. Most days it comes down like a light rain all around me.

There is no big wave. There is no crashing and breaking. Just a slow, steady rain, soaking into everything.

I see death every day, but it doesn't always make for a thrilling story. I see elderly patients over and over, slightly worse each day. I see demanding, high maintenance patients who really only called because they needed someone to talk to, someone to focus on them for a while. I see patients ashamed of themselves. Ashamed of their size, their appearance, or their hygiene. Ashamed that they need us. I see so much sadness. Not the potent sadness of an acute pain or loss. Not the sadness that allows for catharsis. I see a chronic sadness. Less a sharp stab, more a dull ache. A sadness that I don't realize is there until I begin to bend under the weight. Now I'm left searching for the source.

I do look back on certain calls and feel the twinge of the intense feelings that they evoked. I feel regret. I feel guilt. I feel incompetent. At least I feel a sense of understanding. I can understand the hurt of those calls. I can paint a picture in my mind. I can quantify the pain.

Those are not the thoughts running through my mind when I am lost in it all. Instead, I am left here wondering what is causing this. Why am I feeling this way" Why do the highs seem so much lower than they used to be" When did my life become the sum of so many minor injuries"



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When EMS calls leave you with a feeling of emptiness

By Anonymous Paramedic, Sacramento, Calif.

Some days it's a lot to handle. It's a hard thing to describe. I've never been one for talking about my feelings. The more important it is, the more powerful the feeling, the less I will say about it. The best I can do is to say that it is a feeling of crushing emptiness.

There is always a lot of talk about how this job can effect us. People die while we try to keep them from doing so. That is definitely a humbling feeling. I have worn other people's blood on my skin. I have heard the last words of people I have just met. I have felt my paradigm shift, and my ego crumble when I realize that I cannot help my patient and I do not know why.

I have experienced many of the stereotypical, harrowing experiences associated with this profession. I do not mean to underestimate the effects that those experiences can have on us, but for me personally it feels a little self-aggrandizing.

Those are the stories people expect.

When someone sees me staring into space, lost in my thoughts, it's easy for them to imagine those things running through my mind. I wish that were the case.

Make no mistake, I am struggling.

This job does eat away at me every day. There have been days that the toll is taken in one fell swoop, with a fast-paced, high pressure, traumatizing call.

Most days that isn't the case. Most days I don't have such a convenient target to point at when those feelings hit me. Most days it comes down like a light rain all around me.

There is no big wave. There is no crashing and breaking. Just a slow, steady rain, soaking into everything.

I see death every day, but it doesn't always make for a thrilling story. I see elderly patients over and over, slightly worse each day. I see demanding, high maintenance patients who really only called because they needed someone to talk to, someone to focus on them for a while. I see patients ashamed of themselves. Ashamed of their size, their appearance, or their hygiene. Ashamed that they need us. I see so much sadness. Not the potent sadness of an acute pain or loss. Not the sadness that allows for catharsis. I see a chronic sadness. Less a sharp stab, more a dull ache. A sadness that I don't realize is there until I begin to bend under the weight. Now I'm left searching for the source.

I do look back on certain calls and feel the twinge of the intense feelings that they evoked. I feel regret. I feel guilt. I feel incompetent. At least I feel a sense of understanding.  I can understand the hurt of those calls. I can paint a picture in my mind. I can quantify the pain.

Those are not the thoughts running through my mind when I am lost in it all. Instead, I am left here wondering what is causing this. Why am I feeling this way? Why do the highs seem so much lower than they used to be? When did my life become the sum of so many minor injuries?



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Outcomes in colorectal surgeon-driven management of obstructing colorectal cancers

Diseases of the Colon and Rectum

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Cost-effectiveness of emergency versus delayed laparoscopic cholecystectomy for acute gallbladder pathology

British Journal of Surgery

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Cardiopulmonary resuscitation using the Lifeline ARM mechanical chest compression device: A randomized, cross-over, manikin trial

The American Journal of Emergency Medicine

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New SIDS research shows carbon dioxide, inner ear damage may play important role

Seattle Children’s Hospital News

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The use and modification of injury prevention exercise by professional youth soccer teams

Scandinavian Journal of Medicine & Science in Sports

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The beneficial place for the treatment of ruptured abdominal aortic aneurysms

International Journal of Surgery

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Safety and efficacy of non-compliant balloon angioplasty for the treatment of subarachnoid hemorrhage-induced vasospasm: A multicenter study

World Neurosurgery

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Researchers develop system to classify gunshot wounds and other similar injuries to the head

University of Maryland School of Medicine News

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Surgical outcomes for the ruptured hepatocellular carcinoma: Multicenter analysis with a case-controlled study

Journal of Gastrointestinal Surgery

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Low carbohydrate diet impairs the effect of glucagon in the treatment of insulin-induced mild hypoglycemia: A randomized cross-over study

Diabetes Care

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CT Imaging selection in acute stroke

European Journal of Radiology

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Small versus large catheters for ventriculostomy in the management of intraventricular hemorrhage

World Neurosurgery

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Benign paroxysmal positional vertigo secondary to mild head trauma

Annals of Otology, Rhinology & Laryngology

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Role of the renal microcirculation in progression of chronic kidney injury in obesity

American Journal of Nephrology

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Reduction of emergency department visits using an urgent clinic for children with established epilepsy

Neurology® Clinical Practice

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Traumatic diaphragmatic rupture in pediatric age: Review of the literature

European Journal of Trauma and Emergency Surgery

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Factors associated with the over-treatment and under-treatment of gonorrhea and Chlamydia of adolescents presenting to a public hospital emergency department

International Journal of Infectious Diseases

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Study: With Medicaid, ER visits remain high for two years

Massachusetts Institute of Technology Research News

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The squeeze maneuver assisted by indocyanine green videoangiography: A simple technique to resuscitate partially occluded bridging veins during microneurosurgical operations

World Neurosurgery

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Wearable tattoo sends alcohol levels to your cell phone

National Institute of Biomedical Imaging and Bioengineering News

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Τετάρτη 26 Οκτωβρίου 2016

Short-term effects of neuromuscular blockade on global and regional lung mechanics, oxygenation and ventilation in pediatric acute hypoxemic respiratory failure

Neuromuscular blockade (NMB) has been shown to improve outcome in acute respiratory distress syndrome (ARDS) in adults, challenging maintaining spontaneous breathing when there is severe lung injury. We tested...

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Halloween ambulance lightshow

Happy Halloween from AMR Antelope Valley Division | Los Angeles County Operations!

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Does small-volume resuscitation with crystalloids or colloids influence hemostasis and survival of rabbits subjected to lethal uncontrolled hemorrhage?.

Introduction: Prehospital, small-volume resuscitation of combat casualties with a synthetic colloid [6% hydroxyethyl starch (HES) 670/0.75] has been recommended when blood or blood components are unavailable. We studied hemostatic effects of a newer synthetic colloid (6% HES 130/0.4,) compared to either a natural colloid (albumin) or to crystalloids in an uncontrolled hemorrhage model. Methods: Spontaneously breathing NZW rabbits (3.4+/-0.1 kg) were anesthetized, instrumented and subjected to a splenic injury with uncontrolled bleeding. Fifteen minutes after injury, rabbits were in shock (MAP= 26 +/-1.3 mmHg, and received colloids (6% HES 130/0.4 or 5% albumin at 15mL/kg), or crystalloids (normal saline at 30 mL/kg or 5% hypertonic saline at 7.5 mL/kg) for resuscitation in two intravenous bolus injections (15 minutes apart) to raise their MAP to 65 mm Hg, n=9/group. Animals were monitored for 2.5 hrs or until death, and blood losses were measured. Blood samples were analyzed for ABG, CBC, and coagulation measures. Results: There were no differences among groups in baseline measures and initial hemorrhage volume (11.9+/-0.6 mL/kg) at 15 minutes post-injury. Twenty minutes after fluid resuscitation (1hr post-injury), MAP was higher, shock indices were lower and blood pH was higher in colloids vs. crystalloids groups (p

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Epidemiology and outcomes of children with accidental hypothermia: A propensity-matched study.

Background: The purpose of this study was to explore the epidemiology and outcomes of hospitalized children with a diagnosis of accidental hypothermia. Methods: The 2012 Kids' Inpatient Database, detailing discharge diagnoses in children admitted to US hospitals, was analyzed using ICD-9-DM codes to filter out relevant patients. Children ages 1 month to 17 years were included in the analysis. Demographic and outcome variables in the hypothermia group were compared with the rest of the patients. In a separate analysis, children with hypothermia were matched 1:1 using a correlative propensity score utilizing gender, age, hospital region, income quartiles, race, ventilation status, coagulopathy, drowning, and APRDRG severity score and their outcomes were compared with controls. The sample data were weighted to get a national estimate. Results: Accidental hypothermia was present in 1,028 cases out of 1,915,435 discharges. Children with hypothermia were more likely to be males (54.7% vs 50.9%; p

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Details for transfusion in trauma patients.

No abstract available

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Gun Violence is Structural Violence: Our Role as Trauma Surgeons.

No abstract available

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A Legacy of Caring: AAST 75th Annual Meeting Presidential Address.

Senior surgeon leaders have unique knowledge and wisdom that should be shared with the next generation of surgeons. In order to assess the type of wisdom and the best methods of transferring it, 62 senior surgeons with more than 30 years of clinical and leadership experience were interviewed to obtain the answers to eight questions. Replies were transcribed verbatim and qualitative research software was used to determine the most frequent replies. The reasserting of core values by today's surgical leaders is the first step in the transfer of knowledge and wisdom to the next generation of surgeons. The second step is that the leader sets an example by living these core values and holds him/herself accountable to the highest standards especially those relating to patient care. By serving others we carry this wisdom forward, make it part of the next generation's life, and earn our part of a heritage that creates a lasting legacy of caring. (C) 2016 Lippincott Williams & Wilkins, Inc.

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Model of trauma-induced coagulopathy including hemodilution, fibrinolysis, acidosis and hypothermia: Impact on blood coagulation and platelet function.

Background: Trauma-induced coagulopathy (TIC) is commonly seen among patients with severe injury. The dynamic process of TIC is characterized by variability of the features of the disease. Methods: A model of TIC was created. Hemodilution was produced by mixing the blood with 40% TRIS/saline solution, fibrinolysis by treating the blood with 160 ng/mL tPA, acidosis by adding 1.2 mg/mL lactic acid achieving pH 7.0-7.1, and hypothermia by running the assay at 31 [degrees]C. Intact blood tested at 37 [degrees]C served as control. Clot formation was evaluated using rotation thromboelastometry. Platelet adhesion and aggregation were assayed at a shear rate of 1800 s-1 using Impact-R device. Results: Clotting time was not affected by any of the TIC constituents used. Clotting initiation was reduced by hemodilution and further reduced by additive hypothermia. The propagation phase of blood clotting was reduced by hemodilution, further reduced by additive hypothermia, and maximally reduced if additionally combined with fibrinolysis. No effect of fibrinolysis on clot propagation was observed at 37 [degrees]C. Maximum clot firmness was reduced by hemodilution, further reduced by additive fibrinolysis, and maximally reduced if additionally combined with hypothermia. No effect of hypothermia on clot strength was observed in the absence of fibrinolysis. Platelet adhesion (percentage of surface coverage) and aggregation (aggregate size) under flow condition were reduced by hemodilution and further reduced by additive acidosis. Introduction of tPA to diluted blood had no effect on platelet function. Conclusion: The study revealed differential effect of TIC constituents - hemodilution, hypothermia, fibrinolysis, and acidosis - on clot formation and platelet function. The effect of one factor may influence on that of another factor. These data may be helpful to better understanding the pathogenesis of TIC and to elaboration of individually-tailored treatment strategy. Level of evidence: A new model of TIC is created. Contribution of various constituents to pathogenesis of TIC and their interactions are evaluated. (C) 2016 Lippincott Williams & Wilkins, Inc.

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