FACING THE FACTS ON PROPHYLACTIC ANTIBIOTICS FOR FACIAL FRACTURES: ONE DAY OR LESS

Background To evaluate the role of initial prophylactic antibiotics on facial fractures, outcomes were compared between a short course (≤24 hours) of antibiotics to those who received an extended course (>24 hours). Methods Adults admitted (2010–2015) to a level 1 trauma center intensive care unit with at least 1 facial bone fracture and major injuries isolated to the head and neck were included. Our primary analysis compared infectious complications of the head or neck (H/N infection) between patients given short or extended courses of antibiotic prophylaxis. Multivariate logistic regression (MLR) and analysis of propensity score matched pairs were performed. Results A total of 403 patients were included, 85.6% had blunt injuries and 72.7% had their facial fracture managed non-operatively. H/N infection rate was 11.2%. 280 patients received a short course of antibiotics and 123 patients received an extended course. Median ISS was 14 in both groups (p=0.78). Patients receiving an extended course of antibiotics had higher rates of H/N infection (20.3% vs 7.1%, p

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