Objectives: We sought to assess whether the GlideScope Ranger video laryngoscope may be a reliable alternative to direct laryngoscopy in the prehospital setting. Design: Multicenter, prospective, randomized, control trial with patient recruitment over 18 months. Setting: Four study centers operating physician-staffed rescue helicopters or ground units in Austria and Norway. Patients: Adult emergency patients requiring endotracheal intubation. Interventions: Airway management strictly following a prehospital algorithm. First and second intubation attempt employing GlideScope or direct laryngoscopy as randomized; third attempt crossover. After three failed intubation attempts, immediate use of an extraglottic airway device. Measurements and Main Results: A total of 326 patients were enrolled. Success rate with the GlideScope (n = 168) versus direct laryngoscopy (n = 158) group was 61.9% (104/168) -versus 96.2% (152/158), respectively (p
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