The Impact of Acute Coagulopathy on Mortality in Pediatric Trauma Patients.

Background: Traumatic coagulopathy (TC) occurs in 24-38% of adults and is associated with up to a 6-fold increase in mortality. This study's purpose is to determine the incidence of pediatric TC and its impact on mortality. Methods: A retrospective review (2004-2009) of all trauma patients from our Level I Trauma Center was performed. Coagulopathy was defined as an INR >= 1.5 or aPTT > 36 seconds or platelets =16 years). Results: A total of 20,126 patients were identified (7.6% pediatric, 92.4% adult). Mean age +/- SD was 8.7 +/- 4.8 years for pediatric patients and 37.6 +/- 16.7 years for adults. The incidence of admission coagulopathy was lower in children (5.8% vs. 8.4%, p

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