The Association Between Acute Respiratory Distress Syndrome Hospital Case Volume and Mortality in a U.S. Cohort, 2002–2011

Objectives: This study examines the relationships between hospitals’ annual acute respiratory distress syndrome case volume with hospitals’ acute respiratory distress syndrome case fatality rates and individuals’ odds of acute respiratory distress syndrome hospital mortality. Design: Retrospective cohort study. Setting: The U.S. Healthcare Cost and Utilization Project’s Nationwide Inpatient Sample, 2002–2011. Patients: Acute respiratory distress syndrome discharges defined by the presence of an acute respiratory distress syndrome International Classification of Diseases, 9th revision, Clinical Modification diagnosis code (518.82 or 518.5) and a mechanical ventilation procedure code (96.70, 96.71 or 96.72) on the discharge diagnosis and procedure lists. If the procedure code 96.71 was on the discharge record (mechanical ventilation

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