An Introduction to the Most Complex Disease in Emergency Medicine

Sepsis is one of the most complex and challenging diseases in medicine. Timely diagnosis and initiation of therapy are required in order to prevent unnecessary increases in patient morbidity and mortality. Unfortunately, the clinical presentation of sepsis is often nonspecific and may lead to delays in diagnosis and treatment. Since the majority of patients with sepsis initially present to the emergency department, it is imperative for the emergency provider (EP) to be knowledgeable regarding current concepts and controversies in sepsis management.

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