Body Composition Changes in Severely Burned Children During ICU Hospitalization.

Objectives: Prolonged hospitalization due to burn injury results in physical inactivity and muscle weakness. However, how these changes are distributed among body parts is unknown. The aim of this study was to evaluate the degree of body composition changes in different anatomical regions during ICU hospitalization. Design: Retrospective chart review. Setting: Children's burn hospital. Patients: Twenty-four severely burned children admitted to our institution between 2000 and 2015. Interventions: All patients underwent a dual-energy x-ray absorptiometry within 2 weeks after injury and 2 weeks before discharge to determine body composition changes. No subject underwent anabolic intervention. We analyzed changes of bone mineral content, bone mineral density, total fat mass, total mass, and total lean mass of the entire body and specifically analyzed the changes between the upper and lower limbs. Measurements and Main Results: In the 24 patients, age was 10 +/- 5 years, total body surface area burned was 59% +/- 17%, time between dual-energy x-ray absorptiometries was 34 +/- 21 days, and length of stay was 39 +/- 24 days. We found a significant (p

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