Τετάρτη 4 Ιανουαρίου 2017

The occurrence of single and multiple organ dysfunction in pediatric electrical vs. other thermal burns.

Background: Multiple organ failure (MOF) is a major contributor to morbidity and mortality in burned children. While various complications induced by electrical injuries have been described, the incidence and severity of single organ failure (SOF) and MOF associated with this type of injury are unknown. The study was undertaken to compare the incidence and severity of SOF and MOF as well as other complications between electrically and thermally burned children. Patients and Methods: Between 2001 and 2016, two hundred eighty-eight pediatric patients with electrical burns (EB, N=96) or thermal burns (CTR, N=192) were analyzed in this study. Demographic data, length of hospitalization, number and type of operations, amputations, and complications were statistically analyzed. Incidence of SOF and MOF was assessed using the DENVER2 classification in an additive mixed model over time. Compound scores and organ-specific scores for lung, heart, kidney, and liver were analyzed. Serum cytokine expression profiles of both groups were also compared over time. Significance was accepted at p

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