Monitoring of vascular endothelial growth factor and its soluble receptor levels in early trauma.

BACKGROUND: This clinical observation study aimed to investigate the relationship between the serum levels of vascular endothelial growth factor (VEGF) and its soluble receptors with the severity and the occurrence of late acute respiratory distress syndrome (ARDS) in early trauma. METHODS: Sixty patients with multiple trauma were divided into three groups according to the injury severity score (ISS) and the serum levels of VEGF, soluble VEGF receptor 1 (sVEGFR1), and sVEGFR2, were measured. Ten healthy people were recruited as controls. The incidence of late ARDS was also monitored and its relationship to the above measures analyzed. RESULTS: VEGF was not associated with ISS (P > 0.05); sVEGFR1 was positively associated with ISS (r2 = 0.459, P 0.05). sVEGFR1 in the ARDS group was significantly higher than that in the non-ARDS group (P

from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/2jOhIWx