Objective: Patients in PICUs frequently present hypochloremic metabolic alkalosis secondary to loop diuretic treatment, especially those undergoing cardiac surgery. This study evaluates the effectiveness of acetazolamide therapy for metabolic alkalosis in PICU patients. Design: Retrospective, observational study. Setting: A tertiary care children's hospital PICU. Patients: Children receiving at least a 2-day course of enteral acetazolamide. Interventions: None. Measurements and Main Results: Demographic variables, diuretic treatment and doses of acetazolamide, urine output, serum electrolytes, urea and creatinine, acid-base excess, pH, and use of mechanical ventilation during treatment were collected. Patients were studied according to their pathology (postoperative cardiac surgery, decompensated heart failure, or respiratory disease). A total of 78 episodes in 58 patients were identified: 48 were carried out in cardiac postoperative patients, 22 in decompensated heart failure, and eight in respiratory patients. All patients received loop diuretics. A decrease in pH and PCO2 in the first 72 hours, a decrease in serum HCO3- (mean, 4.65 +/- 4.83; p
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Archives of Clinical Neuropsychology from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/2eTSYdQ
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Objective: Many ICU patients do not require critical care interventions. Whether aggressive care environments increase risks to low-acuity p...
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Timing of Gestation After Laparoscopic Sleeve Gastrectomy (LSG): Does it Influence Obstetrical and Neonatal Outcomes of Pregnancies? Ivor Le...
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The American Journal of Emergency Medicine from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/2t0g8pt
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Publication date: December 2018 Source: The Journal of Emergency Medicine, Volume 55, Issue 6 Author(s): Matthew Mendes from Emergency...
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