Objectives: Early posttraumatic seizures may contribute to worsened outcomes after traumatic brain injury. Evidence to guide the evaluation and management of early posttraumatic seizures in children is limited. We undertook a survey of current practices of continuous electroencephalographic monitoring, seizure prophylaxis, and the management of early posttraumatic seizures to provide essential information for trial design and the development of posttraumatic seizure management pathways. Design: Surveys were sent to site principal investigators at all 43 sites participating in the Approaches and Decisions in Acute Pediatric TBI trial at the time of the survey. Surveys consisted of 12 questions addressing strategies to 1) implement continuous electroencephalographic monitoring, 2) posttraumatic seizure prophylaxis, 3) treat acute posttraumatic seizures, 4) treat status epilepticus and refractory status epilepticus, and 5) monitor antiseizure drug levels. Setting: Institutions comprised a mixture of free-standing children's hospitals and university medical centers across the United States and Europe. Subjects: Site principal investigators of the Approaches and Decisions in Acute Pediatric TBI trial. Interventions: None. Measurements and Main Results: Continuous electroencephalographic monitoring was available in the PICU in the overwhelming majority of clinical sites (98%); however, the plans to operationalize such monitoring for children varied considerably. A similar majority of sites report that administration of prophylactic antiseizure medications is anticipated in children (93%); yet, a minority reports that a specified protocol for treatment of posttraumatic seizures is in place (43%). Reported medication choices varied substantially between sites, but the majority of sites reported pentobarbital for refractory status epilepticus (81%). The presence of treatment protocols for seizure prophylaxis, early posttraumatic seizures, posttraumatic status epilepticus, and refractory status epilepticus was associated with decreased reported medications (all p
from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1U0B3A2
Εγγραφή σε:
Σχόλια ανάρτησης (Atom)
Δημοφιλείς αναρτήσεις
-
International Journal of Environmental Research... Latest Results for Sleep and BreathingIntermitt... Evolutionary Biology News -- S...
-
Big dreams to improve EMS with a windfall of funding for safety, health and wellness, research and leadership development from EMS via xlo...
-
No abstract available from Emergency Medicine via xlomafota13 on Inoreader http://ift.tt/1ZlzU7L
-
Abstract Background Angiogenesis is an indispensable step in the growth and invasiveness of breast cancers involving a series of exquisi...
-
In Finland, calls for emergency medical services are prioritized by educated non-medical personnel into four categories—from A (highest risk...
-
Zusammenfassung Hintergrund Die Störung der Blut-Hirn-Schranke – gemessen mittels Magnetresonanztomographie – stellt kein zuverlässiges ...
-
Learn how to recognize the signs of sudden cardiac arrest and to administer CPR in less than 5 minutes. from EMS via xlomafota13 on Inorea...
Δεν υπάρχουν σχόλια:
Δημοσίευση σχολίου