Κυριακή 2 Απριλίου 2017
Department's first therapy cat just makes things worse
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Σάββατο 1 Απριλίου 2017
EM Nerd-The Case of the Bridge to Nowhere
The use of mechanical cardiopulmonary resuscitation (mCPR) has been a polarizing topic almost from its inception. The idea, a simple one. Why not build a machine that is capable of doing perfect chest compressions? A simple, effective way to eliminate the inconsistencies common to manual chest compressions. And yet, despite building a number of devices […]
EMCrit by Rory Spiegel.
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EM Nerd-The Case of the Bridge to Nowhere
The use of mechanical cardiopulmonary resuscitation (mCPR) has been a polarizing topic almost from its inception. The idea, a simple one. Why not build a machine that is capable of doing perfect chest compressions? A simple, effective way to eliminate the inconsistencies common to manual chest compressions. And yet, despite building a number of devices […]
EMCrit by Rory Spiegel.
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Validity of the Pediatric Canadian Triage Acuity Scale in a tertiary children's hospital in Israel.
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The De Winter ECG pattern: morphology and accuracy for diagnosing acute coronary occlusion: systematic review.
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Direct Versus Video Laryngoscopy for Prehospital Intubation: A Systematic Review and Meta-analysis
Abstract
Objectives
The use of video laryngoscopy (VL) for intubation has gained recent popularity. In the prehospital setting, it is unclear if VL increases intubation success rates compared to direct laryngoscopy (DL). We sought to conduct a systematic review and meta-analysis of studies comparing VL to DL in the prehospital setting to determine whether the use of VL increases overall and first-pass endotracheal intubation success rates compared to DL.
Methods
A systematic search was performed of the Pubmed, Embase, and SCOPUS databases through May 2016 to include studies comparing overall and first-pass success for VL vs. DL in patients requiring intubation in the prehospital setting. Data were abstracted by two reviewers. A meta-analysis was performed using a random effects model.
Results
Of a potential 472 articles, eight eligible studies were included. Considerable heterogeneity (I2 > 90%) precluded reporting an overall pooled estimate across all studies. When stratified by provider type, the pooled estimate for overall intubation success using VL vs. DL was RR = 0.05 (95% CI 0.01, 0.18) in studies of physicians and RR = 2.28 (95% CI 1.00, 5.20) in non-physicians. For first-pass intubation success the pooled RR estimate for using VL vs. DL was 0.32 (95% CI 0.23, 0.44) and 1.83 (95% CI 1.18, 2.84) among studies using physicians and non-physicians, respectively. There was moderate to significant heterogeneity between studies when stratified by provider.
Conclusions
Among physician intubators with significant DL experience, VL does not increase overall or first-pass success rates and may lead to worsening performance. However, among non-physician intubators with less experience with DL, VL may provide benefit in the prehospital setting.
This article is protected by copyright. All rights reserved.
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D-Dimer Interval Likelihood Ratios for Pulmonary Embolism
Abstract
Objective
To estimate D-Dimer interval likelihood ratios (iLRs) for diagnosing pulmonary embolism (PE).
Methods
The authors used pooled patient-level data from five PE diagnostic management studies to estimate iLRs for the eight D-Dimer intervals with boundaries 250, 500, 750, 1000, 1500, 2500, and 5000 ng/mL. Logistic regression was used to fit the data so that an interval increase corresponds to increasing the likelihood ratio by a constant factor.
Results
The iLR for the D-Dimer interval 1000-1499 ng/mL was essentially 1.0 (0.98 with 95% CI 0.82-1.18). In the logistic regression model, the constant between-interval factor was 2.0 (95% CI 1.9 to 2.1). Using these iLR estimates, if the pre-D-Dimer probability of PE is 15%, only a D-Dimer less than 500 ng/mL will result in a post-test probability below 3%; if the pre-test probability is 5%, the threshold for a “negative” D-Dimer is 1000 ng/mL.
Conclusions
A decision strategy based on these approximate iLRs agrees with several published strategies.
This article is protected by copyright. All rights reserved.
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