Principles, potential and limitations of ex vivo basophil activation by flow cytometry in allergology: a narrative review.

gnorimies2015 shared this article with you from Inoreader Principles, potential and limitations of ex vivo basophil activation by flow cytometry in allergology: a narrative review. Via Journal of Allergy and Clinical Immunology The major challenge of allergy diagnosis lies in the development of accessible and reliable diagnostics allowing correct prediction of the clinical outcome upon exposure to the offending allergen(s) and cross-reactive structures. Since the late nineties, evidence has accumulated that flow-assisted analysis and quantification of ex vivo activated basophils (BAT) might meet this requirement for different IgE-dependent allergies and particular forms of auto-immune urticaria. Other, so called non-diagnostic applications of the BAT involve therapeutic monitoring, follow-up of natural histories and identification of allergenic recognition sites. View on the web Inoreader. Take back control of your news feed. Follow us on Twitter and Facebook.