Symptomatic HIV-Infected Patients Have Poorer Outcomes Following Emergency General Surgery: A Study of the Nationwide Inpatient Sample

BACKGROUND The impact of HIV infection on outcomes following common emergency general surgery procedures has not been evaluated since the widespread introduction of highly-active antiretroviral therapy (HAART). METHODS A retrospective cohort study was conducted using the Nationwide Inpatient Sample. Records of patients who underwent laparoscopic or open appendectomy, cholecystectomy, or colon resection after emergency admission from 2004-2011 were obtained. Outcomes analyzed included in-hospital mortality, length of stay, total charges, and selected postoperative complications. Patients were divided among three groups, HIV negative controls, asymptomatic HIV positive patients and symptomatic HIV/AIDS patients. Data were analyzed using chi-square and multivariable regression with propensity score matching among the three groups, with p

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