Aortic Branch Vessel Flow During Resuscitative Endovascular Balloon Occlusion of the Aorta

Background REBOA (Resuscitative Endovascular Balloon Occlusion of the Aorta) is a torso hemorrhage control adjunct. Aortic branch vessel flow (BVF) during REBOA is poorly characterized and has implications for ischemia-reperfusion (I-R) injury. The aim of this study is to quantify branch vessel flow in hypovolemic shock with and without REBOA. Methods Female swine (79-90kg) underwent anesthesia, 40% controlled hemorrhage and sonographic flow monitoring of the carotid, hepatic, superior mesenteric, renal and femoral arteries. Animals were randomized to REBOA (n=5) or no-REBOA (n=5) for 4 hours, followed by full resuscitation and balloon deflation for 1-hour. Results All animals were successfully induced into hemorrhagic shock with a mean decrease of flow in all vessels of 50% from baseline (p

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