ABSTRACTBackgroundOver 50,000 homicides and suicides occur each year. An estimated half of all U.S. households are believed to have a firearm present, making them one of the most ubiquitous consumer products. Our goal was to determine if the manner of storage of a firearm in a home could potentially make a difference in the outcomes of intentional and unintentional injuries involving a firearm; specifically addressing the use of gun safes and devices that block/disable firearm function (trigger locks, cable locks, etc.).MethodsA comprehensive review of the literature was performed. We used GRADE (Grading of Recommendations Assessment, Development, and Evaluation) methodology to assess the breadth and quality of the data specific to our PICO (Population, Intervention, Comparator, Outcomes) questions.ResultsA total of 176 studies were initially identified, then 120 more added after a subsequent, literature review with 97 removed as duplicates. One hundred and ninety-one case reports, case series, and reviews were removed because they did not focus on prevention or did not address our comparators of interest. This left a total of two studies which merited inclusion for PICO #1, should gun locks be used to prevent firearm injuries and six studies which merited inclusion for PICO #2, should safe storage for guns be used to prevent firearm injuries.ConclusionPICO 1: We conditionally recommend that gun locks be used to prevent unintentional firearm injury.PICO 2: Because of the large effect size and the reasonable quality of available evidence with safe storage of firearms, we recommend safe storage prevent firearm-related injuries.Level of EvidenceSystematic review, level III Background Over 50,000 homicides and suicides occur each year. An estimated half of all U.S. households are believed to have a firearm present, making them one of the most ubiquitous consumer products. Our goal was to determine if the manner of storage of a firearm in a home could potentially make a difference in the outcomes of intentional and unintentional injuries involving a firearm; specifically addressing the use of gun safes and devices that block/disable firearm function (trigger locks, cable locks, etc.). Methods A comprehensive review of the literature was performed. We used GRADE (Grading of Recommendations Assessment, Development, and Evaluation) methodology to assess the breadth and quality of the data specific to our PICO (Population, Intervention, Comparator, Outcomes) questions. Results A total of 176 studies were initially identified, then 120 more added after a subsequent, literature review with 97 removed as duplicates. One hundred and ninety-one case reports, case series, and reviews were removed because they did not focus on prevention or did not address our comparators of interest. This left a total of two studies which merited inclusion for PICO #1, should gun locks be used to prevent firearm injuries and six studies which merited inclusion for PICO #2, should safe storage for guns be used to prevent firearm injuries. Conclusion PICO 1: We conditionally recommend that gun locks be used to prevent unintentional firearm injury. PICO 2: Because of the large effect size and the reasonable quality of available evidence with safe storage of firearms, we recommend safe storage prevent firearm-related injuries. Level of Evidence Systematic review, level III Conflicts of Interest and Sources of Funding: none Corresponding Author: Marie Crandall, MD, MPH, FACS, Professor of Surgery, Director of Research, University of Florida College of Medicine Jacksonville, 655 W. 8th Street, Jacksonville, FL 32209, 904 244 6631 (o), 904 244 3415 (f), Marie.crandall@jax.ufl.edu © 2018 Lippincott Williams & Wilkins, Inc.
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