Gender dysphoria, or the distress caused by the incongruence between a person’s assigned and experienced gender, can lead to significant psychosocial sequelae and increased risk of suicide (>40% of population) and assault (>60% of population). With an estimated 25 million transgender individuals worldwide and increased access to care for the transgender population, trauma surgeons are more likely to care for patients that completed or are in the process of medical gender transition. As transgender health is rarely taught in medical education, knowledge of the unique healthcare needs and possible alterations in anatomy is critical to appropriately and optimally treat transgender trauma victims. Considerations of cross-gender hormones and alterations of the craniofacial, laryngeal, chest, and genital systems are offered in this review. Further research on the optimal treatment mechanisms for transgender patients are needed. Study Type: Review/Guidelines Level of Evidence: V Corresponding Author: Samuel Mandell MD, MPH, FACS, Division of Trauma, Critical Care, and Burn, University of Washington Department of Surgery, Harborview Medical Center, 325 9th Avenue, Mailstop #359796, Seattle, WA 98104, Email: mandells@uw.edu Author Disclosure: Authors have no financial disclosures to declare and there was no funding obtained for the production of this article. © 2018 Lippincott Williams & Wilkins, Inc.
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