Background: The Air Medical Prehospital Triage (AMPT) score was developed to identify injured patients who may benefit from scene helicopter emergency medical services (HEMS) transport. External validation using a different dataset is essential to ensure reliable performance. The study objective was to validate the effectiveness of the AMPT score to identify patients with a survival benefit from HEMS using the Pennsylvania Trauma Outcomes Study (PTOS) registry. Methods: Patients age>=16years undergoing scene HEMS or ground EMS (GEMS) transport in the PTOS registry 2000-2013 were included. Patients with >=2 AMPT score points were triaged to HEMS, while those with 10mins. Results: There were 222,827 patients included. For patients triaged to GEMS by the AMPT score, actual transport mode was not associated with survival (adjusted relative risk [ARR] 1.004; 95%CI 0.999-1.009, p=0.08). For patients triaged to HEMS by the AMPT score, actual HEMS transport was associated with a 6.7% increase in the relative probability of survival (ARR 1.067; 95%CI 1.040-1.083, p
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