Background: Determination and reporting of disease severity in emergency general surgery (EGS) lacks standardization. Recently, the American Association for the Surgery of Trauma (AAST) proposed an anatomic severity grading system. We aimed to validate this system in patients with appendicitis, and determine if cross sectional imaging correlates with disease severity at operation. Methods: Patients 18 years or older undergoing treatment for acute appendicitis between 2013 and 2015 were identified. Baseline demographics, procedure types were recorded, and AAST grades were assigned based on intraoperative and radiologic findings. Outcomes including length of stay, 30 day mortality, and complications based on Clavien-Dindo categories and National Surgical Quality Improvement Program variables. Summary statistical univariate, nominal logistic and standard least squares analyses were performed comparing AAST grade with key outcomes. Bland-Altman analysis compared operative findings to preoperative cross sectional imaging to compare assigning grades. Results: 334 patients with mean (+/-SD) age of 39.3 years (+/-16.5) were included (53% male) and all patients had cross sectional imaging. 299 underwent appendectomy, and 85% completed laparoscopic. 30 day mortality rate was 0.9%, complication rate 21%. Increased median [IQR] AAST grade was recorded in patients with complications 2 [1-4] compared to those without 1 [1-1], p=0.001. For operative management, a median [IQR] AAST grades were significantly associated with procedure type: laparoscopic 1 [1-1], open 4 [2-5] conversion to open 3 [1-4], p=0.001. Increased median [IQR] AAST grades were significantly associated in non-operative management: patients having a complication had a higher median AAST grade of 4 [3-5], compared to those without 3 [2-3], p=0.001. Bland Altman analysis comparing AAST grade and cross sectional imaging demonstrated no difference; -0.02 +/-0.02 p = 0.2 coefficient of repeatability 0.9. Conclusions: The AAST grading system is valid in our population. Increased AAST grade is associated with open procedures, complications, and length of stay. AAST EGS grade determined by preoperative imaging strongly correlated to operative findings. Level of evidence: Level V - Retrospective Study Study type: Retrospective single institution study (C) 2016 Lippincott Williams & Wilkins, Inc.
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[PDF] Καρκίνος του στομάχου -- Αλέξανδρος Γ. Σφακιανάκης Αναπαύσεως 5 Άγιος Νικόλαος Λασιθίου 72100 2841026182
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