Despite their ubiquitous use, proton pump inhibitors (PPI) for the prophylactic prevention of stress ulcer formation in mechanically ventilated patients admitted to the intensive care unit (ICU) have minimal evidence supporting their use. In fact, no single study has ever demonstrated the superiority of PPIs when compared to an H2-blocker or even a placebo (1). […]
EMCrit by Rory Spiegel.
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